Cytosis can be used to teach everything from base editing to RNA editing to everyone over age 10. They will learn how to link the creation of energy to biophysically constrained viral latency via the physiology of pheromone-controlled reproduction.

Ecological adaptations vs the randomness of evolution (4)

Biohacker Aaron Traywick Found Dead in DC Float Spa
He was found face down in a flotation tank.  Timothy J. Cunningham (CDC) was found after he supposedly drowned in a river.
Both had already linked the virus-driven degradation of messenger RNA to all pathology, and both probably knew that vaccines could not protect human populations from the threat of the next viral apocalypse.
Researchers from South Korea recently exposed the facts.
See: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events
and
A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses
SARCASM ALERT: If I told you anything more about this, I would have to kill myself.

Caption: Contemporary analyses of cell metabolism have called out three metabolites: ATP, NADH, and acetyl-CoA, as sentinel molecules whose accumulation represent much of the purpose of the catabolic arms of metabolism and then drive many anabolic pathways. Such analyses largely leave out how and why ATP, NADH, and acetyl-CoA (Figure 1) at the molecular level play such central roles. Yet, without those insights into why cells accumulate them and how the enabling properties of these key metabolites power much of cell metabolism, the underlying molecular logic remains mysterious. Four other metabolites, S-adenosylmethionine, carbamoyl phosphate, UDP-glucose, and Δ2-isopentenyl-PP play similar roles in using group transfer chemistry to drive otherwise unfavorable biosynthetic equilibria. This review provides the underlying chemical logic to remind how these seven key molecules function as mobile packets of cellular currencies for phosphoryl transfers (ATP), acyl transfers (acetyl-CoA, carbamoyl-P), methyl transfers (SAM), prenyl transfers (IPP), glucosyl transfers (UDP-glucose), and electron and ADP-ribosyl transfers (NAD(P)H/NAD(P)+) to drive metabolic transformations in and across most primary pathways. The eighth key metabolite is molecular oxygen (O2), thermodynamically activated for reduction by one electron path, leaving it kinetically stable to the vast majority of organic cellular metabolites

Ecological Adaptations vs the Randomness of Evolution (2)

Summary: See for comparison: Make ‘Em Resistant to Viruses

In the new proposal — which Science says was released in advance of a meeting today — GP-write leaders say “ultrasafe” cells could be developed by making some 400,000 changes to the human genome.

A Fast OneStep Digestion of DNA or RNA for Global Detection and Characterization of Nucleotide Modifications (link opens pdf)
Product information:

The Nucleoside Digestion Mix is an optimized mixture of enzymes that provides a convenient one-step method to generate single nucleosides from DNA or RNA for quantitative analysis by liquid chromatography-mass spectrometry (LC-MS), eliminating the need for sequential multi-step, time-consuming digestion protocols.

Digests both DNA and RNA to single nucleosides

A source of anti-entropic energy is required to create nucleosides and nucleotides. The quantized energy as information was available to modify nucleotides after the creation of sunlight.
See also: Nucleoside vs. Nucleotide

A nucleoside consists of a nitrogenous base covalently attached to a sugar (ribose or deoxyribose) but without the phosphate group. A nucleotide consists of a nitrogenous base, a sugar (ribose or deoxyribose) and one to three phosphate groups.

Nucleoside = Sugar + Base
Nucleotide = Sugar + Base + Phosphate

The link from the”optimized mixture of enzymes” to Digestion of DNA or RNA links the quantification of epigenetic modifications and the activity of nucleic acid modifying enzymes from energy-dependent microRNA biogenesis to the functional structure of cellular RNA, which has been linked to viral latency and ecological adaptations in all living genera.
The facts about the energy-dependent creation of microRNAs and ecological adaptations have been placed into the context of High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development.

These data are provided in easily accessible formats for both craniofacial researchers and clinicians to aid future experimental design and interpretation of noncoding variation in those affected by craniofacial abnormalities.

The facts were reported in Blueprint for the skull: A search for cleft palate’s cause reveals a map of the facial genome

He studies the human genome, but not the genes that tell the body what proteins to make. Instead, he focuses on regulators, parts of the DNA that tell genes when and where to act. These regulators, also known as enhancers, tend to be linked to specific parts of the body.

microRNA cleft palate
1 of 33: A functional polymorphism in the pre-miR-146a gene is associated with the risk of nonsyndromic orofacial cleft.
enhancer cleft palate
1 of 35 Genome-Wide DNA Methylation Analysis During Palatal Fusion Reveals the Potential Mechanism of Enhancer Methylation Regulating Epithelial Mesenchyme Transformation.
The link from the energy-dependent creation of microRNAs to food energy-dependent genome-wide RNA-directed DNA methylation is perfectly clear until the term enhancer is used in the context of a potential mechanism regulating epithelial mesenchyme transformation.
The conserved molecular mechanisms of energy-dependent epigenetically-effected cell type differentiation are missing and the substitution of a potential mechanism of methylation can be used to support neo-Darwinian nonsense about mutation-driven evolution.
Even after pseudoscientists admit that their theories of craniofacial development are ridiculous, since development is energy-dependent and epigenetically effected, they try to place their findings back into the context of gene-centric theories.
Alternatively, they must know that the virus-driven theft of quantized energy links Zika virus-damaged DNA to craniofacial development with the most severe effects on the size of the brain and skull.
See also: Incomplete host immunity favors the evolution of virulence in an emergent pathogen

Partially protective vaccination can sometimes select for increasingly virulent pathogens.

Reported as: In nature, an imperfect immune system drives the evolution of deadly pathogens

As annual flu shot patrons know, immune systems are not perfect and must be constantly reinforced to protect against rapidly evolving pathogens.

Also:

…birds that eat at feeders are more likely to be infected with the disease, which causes red, swollen eyes and often blindness that results in death.

The link from what the birds and the bees eat to healthy longevity was detailed in my 2013 refutation of neo-Darwinian pseudoscientific nonsense.

Nutrient-dependent/pheromone-controlled adaptive evolution: a model

Scientific creationists in the US have started to tout my model without attribution.
See: Are Evolution and Adaptation the Same? 

Mechanisms of adaptation are made up of complex integrated components, including environmental sensors, signaling pathways, feedback and feed-forward loops, and information control systems in the creature’s DNA.

See also: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (2014)
See for comparison: Next-generation diagnostics with CRISPR

The sentinel discovery that prokaryotes (bacteria and archaea) have heritable adaptive immunity mediated through CRISPR and CRISPR-associated (Cas) proteins has led to transformative advances in molecular biology, most notably in gene editing (2).

The discovery of heritable adaptive immunity ended the pseudoscientific nonsense about mutation-driven evolution. It linked vaccinations and gene editing to unpredictable outcomes in species from microbes to humans by altering the perfection of our innate immune system. The alterations link the virus-driven degradation of our messenger RNA to all pathology.
But see: Cytosis for ages 10+

A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!

See for comparison: Make ‘Em Resistant to Viruses

In the new proposal — which Science says was released in advance of a meeting today — GP-write leaders say “ultrasafe” cells could be developed by making some 400,000 changes to the human genome.

512zS1RWlQL._SX331_BO1,204,203,200_

Ecological Adaptations vs the Randomness of Evolution

Summary: Ecological variation is linked to ecological adaptations in all living genera via the creation of microRNAs and the sense of smell.

Odor Perception on the Two Sides of the Brain: Consistency Despite Randomness

Highlights

  • •A random model predicts observed preservation of correlations in piriform responses
  • •The model supports consistent agreement about odor quality among individuals

The model fails to explain how the energy-dependent creation of microRNAs links pattern recognition to the creation of pre-mRNAs and biophysically constrained viral latency. Everything required for our visual perception of energy and mass in the context of the space-time continuum has been linked to the RNA-mediated transgenerational epigenetic inheritance of conserved molecular mechanisms.

See: Minding your caps and tails

A nascent mRNA, synthesized in the nucleus, undergoes different modifcations before it can be translated into proteins in the cytoplasm. For a mRNA to be functional, it requires modifed 5´ and 3´ ends and a coding region (i.e., an open reading frame (ORF) encoding for the protein of interest) flanked by the untranslated regions (UTRs). The nascent mRNA (premRNA) undergoes two signifcant modifcations in addition to splicing.

Simply put, nascent mRNAs do not exist outside the context of their energy-dependent creation.

See also:  Feedback loops link odor and pheromone signaling with reproduction (2005)

Mathematical models explain nothing when they fail to link the anti-entropic virucidal of sunlight to energy-dependent RNA-mediated biophysically constrained viral latency.

Linda Buck shared the 2004 Nobel Prize in Physiology and Medicine with Richard Axel, who is a co-author of the article about consistency despite randomness. She is scheduled to present during Schrödinger at 75 – The Future of Biology – September 2018

For comparison, Richard Axel appears to have been stuck with ridiculous theories and mathematical models.

See also: Are Evolution and Adaptation the Same?

Evolutionists believe adaptable traits arose through the progressive accumulation of random genetic mutations that somehow provided an advantage to living things facing specific environmental challenges. But not only are nearly all mutations either harmful or at best neutral, it’s impossible to achieve a functioning system of many orchestrated components one step at a time. All-or-nothing systems cannot evolve bit by bit.

Ecological variation is linked to ecological adaptations in all living genera via the creation of microRNAs and the sense of smell.

See: Olfaction Warps Visual Time Perception

See also: Energy as information and constrained endogenous RNA interference

Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements.

The rearrangements link energy-dependent fixed amino acid substitutions to the Precision Medicine Initiative via genome wide inferences of natural selection. This detailed representation of energy-dependent natural selection for codon optimality links biologically- based cause and effect from G protein-coupled receptors to RNA-mediated amino acid substitutions and the functional structure of supercoiled DNA.

Energy-dependent polycombic ecological adaptations are manifested in supercoiled DNA. Chromosomal inheritance links the adaptations from morphological phenotypes to healthy longevity via behavioral phenotypes. For contrast, virus-driven energy theft is the link from messenger RNA degradation to negative supercoiling, constraint breaking mutations, and hecatombic evolution. The viral hecatomb links transgenerational epigenetic inheritance from archaea to Zika virus-damaged DNA, which typically is repaired by endogenous RNA interference and fixation of RNA-mediated amino acid substitutions in organized genomes

5th-6th Sept 2018 Dublin, Ireland

MicroRNA-mediated autophagy, denuclearization and eusociality

Altruism in a volatile world

reported as: The Elusive Calculus of Insects’ Altruism and Kin Selection

In 1964, the evolutionary biologist William D. Hamilton seemingly explained one of the greatest paradoxes in biology with a simple mathematical equation.

He will be remembered by all serious scientists for his ignorance of top-down energy-dependent causation.
For comparison, McEwen et al. (1964), explained energy-dependent ecological adaptation and sympatric speciation by starting with the energy-dependent creation of RNA.
See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

Last year, the cell biology game “Cytosis” allowed ages 10+ to link ATP from the creation of RNA to biophysically constrained viral latency in all living genera.
Neo-Darwinian theorists still refuse to learn anything about viral latency. They think in terms of chronological clues rather than facts about energy-dependent gene transfers.

See: Chronological Clues to Life’s Early History Lurk in Gene Transfers

Traditionally, scientists have relied on “rocks and clocks” to date the tree of life: fossil evidence from the geological record, and “molecular clock” estimates that infer how long ago related species diverged by analyzing the rate at which mutations built up in their genomic sequences. But there’s a problem: Molecular clock rates differ between lineages — they’re much faster in rodents than in primates, for instance — so if they’re not calibrated against fossil data, they can lead to the wrong conclusions.

For comparison, see: Research: A comprehensive and quantitative exploration of thousands of viral genomes

Existing viral classification systems were developed prior to the sequencing era, so we present our analysis in a way that allows us to assess the utility of the different classification systems for capturing genomic trends.

Genomic trends? See for comparison: MicroRNA Regulation of RNA Virus Replication and Pathogenesis

…the development of a miRNA therapeutic for Ebola virus was used during the recent outbreak in Africa. However testing was ultimately suspended, as the drug did not demonstrate a significant role in patient recovery [78]. Also, insertion of tissue-specific miRNA binding sites have been used as an effective mechanism to prevent virus replication in particular tissues as an attenuation mechanism for vaccines, helping to limit adverse events [79]. Furthermore, recent evidence suggests the presence of viral-derived small RNAs during infection of both mammalian and arthropod cells [80,81]. While controversial, their presence and function during animal infections will need to be further examined. Viral interactions with the miRNA system can affect cellular miRNA and transcriptome levels as well as virus replication within a cell expressing a miRNA; these may indirectly modulate cytokine expression and tissue responses throughout an infected host.

Genetic transcription ‘pause’ is focus of NASA grant

The pause – which was first discovered 30 years ago by Cornell molecular biologist and geneticist John Lis – is a step in transcription where the enzyme RNA polymerase II begins transcribing and then is halted partway through the process and held in place by a specific .

The “pause” links seemingly futile cycles of microRNA biogenesis to the creation of enzymes and alternative splicings of pre-mRNAs (aka microRNAs). Energy-dependent changes in the microRNA/messenger RNA balance link the fixation of amino acid substitutions in proteins to healthy longevity via the physiology of pheromone-controlled reproduction in species from microbes to humans.
Simply put, the pause links autophagy to biophysically constrained viral latency and sympatric speciation. The length of the pause is quantized energy-dependent and/or biophysically constrained food energy-dependent. It ensures that enough energy is available for cell type differentiation to proceed so that the organized genome is protected from the virus-driven degradation of messenger RNA that links mutations to all pathology.
When atheistic Communist researchers learned that vaccines could not protect them from a genetically engineered virus that could be created to target human populations in North Korea and China, denuclearization was virtually ensured. The threat of a viral apocalypse is far greater than the threat of another land war in Asia or the nuclear threat.
In the end, everyone will learn what life is about after review of “What is Life? (1944) and my comments here:

Caption: Contemporary analyses of cell metabolism have called out three metabolites: ATP, NADH, and acetyl-CoA, as sentinel molecules whose accumulation represent much of the purpose of the catabolic arms of metabolism and then drive many anabolic pathways. Such analyses largely leave out how and why ATP, NADH, and acetyl-CoA (Figure 1) at the molecular level play such central roles. Yet, without those insights into why cells accumulate them and how the enabling properties of these key metabolites power much of cell metabolism, the underlying molecular logic remains mysterious. Four other metabolites, S-adenosylmethionine, carbamoyl phosphate, UDP-glucose, and Δ2-isopentenyl-PP play similar roles in using group transfer chemistry to drive otherwise unfavorable biosynthetic equilibria. This review provides the underlying chemical logic to remind how these seven key molecules function as mobile packets of cellular currencies for phosphoryl transfers (ATP), acyl transfers (acetyl-CoA, carbamoyl-P), methyl transfers (SAM), prenyl transfers (IPP), glucosyl transfers (UDP-glucose), and electron and ADP-ribosyl transfers (NAD(P)H/NAD(P)+) to drive metabolic transformations in and across most primary pathways. The eighth key metabolite is molecular oxygen (O2), thermodynamically activated for reduction by one electron path, leaving it kinetically stable to the vast majority of organic cellular metabolites

Virus-driven cystinosis

A friend asked about nephropathic cystinosis, which is a disease caused by the virus-driven theft of quantized energy. All serious scientists have linked viruses from the degradation of messenger RNA to mutations and all pathology.

Nephropathic cystinosis (NC) is the most frequent cause of Fanconi syndrome (FS) in young children. It will be linked from the virus-driven degradation of messenger RNA to azoospermia and/or progressive neuromuscular degeneration via the conserved molecular mechanisms of RNA-mediated cell type differentiation compared to mechanisms that link viruses to mitochondrial degeneration.

See: Impact of atypical mitochondrial cyclic-AMP level in nephropathic cystinosis

Treatment with the non-hydrolysable cAMP analog 8-Br-cAMP restored mitochondrial potential and corrected mitochondria morphology. Treatment with cysteamine, which reduces the intra-lysosomal cystine, was able to restore mitochondrial cAMP levels, as well as most other abnormal mitochondrial findings.

The link to treatment of the atypical mitochondrial cyclic-AMP level has not yet been detailed because biologically uninformed science idiots have linked mutations to evolution. But see: Combating Evolution to Fight Disease  and the preprint: Reappraising the human mitochondrial DNA recombination dogma 

The facts about human mitochondrial DNA recombination, which link quantized energy and supercoiled DNA to viral latency, played a significant role in North Korea’s denuclearization. But that fact may not be accepted until the article on human mitochondrial DNA recombination is published in a peer-reviewed journal.

It will then take several more years for medical practitioners to learn how to effectively treat all diseases with food energy-dependent changes in the microRNA/messenger RNA balance.

See for details: Energy as information and constrained endogenous RNA interference

Until all pseudoscientists accept the facts, there will be many others who try to profit from misinformation or from partial information about virus-driven pathology. Most people will not read my reviews and journal articles like this:  MicroRNA Regulation of RNA Virus Replication and Pathogenesis

Instead, most are willing to accept the claims of others who have “blown the whistle” on vaccines more than two decades after I first published this review of RNA-mediated cell type differentiation in a peer-reviewed journal. From Fertilization to Adult Sexual Behavior

See:  Doctor Blows Whistle on Flu Shot: ‘It’s Designed to Spread Cancer’

Treague confirmed that this year’s flu strain, that has left thousands of citizens dead, was caused by the vaccines itself, saying: “I believe that the low effective rate of the vaccine this year is due to the mutations that the virus made in the processing of the vaccine itself.

Claims that viruses make mutations are the claims of fools who do not know that the virus-driven degradation of messenger RNA has been linked from mutations to all pathology in more than 72,000 published works.

See: microRNA

An evolutionary theory killer

Environmental selection is natural selection (6)

You Don’t Know GMOs

We’re working with a team of geneticists, biologists, and environmental scientists to bring you the most up-to-date report on the science, history, and safety of genetically-modified organisms.

Coming May 2018

I know how GMOs are linked to the forthcoming viral apocalypse. Do you? Atheistic communists in North Korea have learned. When will you?

See also: POWER OF FOOD

….a challenge to prepare a dish that could be scalable for thousands of people as part of post-disaster relief efforts.
Watering Young Plant - Vintage Effect

Environmental selection is natural selection (5)

Summary: Atheistic Chinese Communists realize that vaccinations cannot protect them. Their attempts to develop a universal vaccine have failed. Bill Gates promotes vaccinations, which led us to the brink of the next pandemic.

Vaccines prevent ecological adaptations in some cell types. Does Bill Gates, a non-scientist, think that people from God-fearing non-communist countries can do better than the atheistic Communists?

Bill Gates calls on U.S. to lead fight against a pandemic that could kill 33 million

Gates and his wife, Melinda, have repeatedly warned that a pandemic is the greatest immediate threat to humanity. Experts say the risk is high, because new pathogens are constantly emerging and the world is so interconnected.

New pathogens do not emerge. Read Quantico. The viruses that cause all pathology ecologically adapt by stealing the quantized energy that all differentiated cell types need to survive.

Bill Gates thinks a coming disease could kill 30 million people within 6 months — and says we should prepare for it as we do for war

If you were to tell the world’s governments that weapons that could kill 30 million people were under construction right now, there’d be a sense of urgency about preparing for the threat, Gates said.

The one time the military tried a sort of simulated war game against a smallpox pandemic, the final score was “smallpox one, humanity zero,” Gates said.

See also: Nov 17, 2016 Obama Advisers Urge Action Against CRISPR Bioterror Threat

…a strategy was developed in 2009, but it’s carried out by several government agencies in an uncoördinated approach…

Bill Gates has been promoting vaccinations as a strategy. The vaccinations led us to the brink of the pandemic. Vaccines prevent ecological adaptations in some cell types. The atheistic Chinese Communists now realize that vaccinations cannot protect them. Their attempts to develop a universal vaccine have failed, miserably. Does Bill Gates, a non-scientist, think that people from non-communist countries can do better than the atheistic Communists?
Perhaps he doesn’t know how South Korea forced the denuclearization of North Korea, which will probably lead to proclamations of world peace.
See: Engineered virus has artificial amino acid allowing it to serve as a vaccine (2016)

A team of researchers at Peking University has developed a new type of vaccine that they claim may allow for a new approach to generating live virus vaccines which could conceivably be adapted to any type of virus.

Their “new approach” failed. The uncoordinated strategy against the CRISPR bioterror threat has failed to address the established scientific facts. All ecological adaptations are quantized energy-dependent and biophysically constrained by the physiology of pheromone-controlled reproduction in species from microbes to humans. That fact is presented in the context of the Holy Bible, which explains why scientific creationists from South Korea were able to force denuclearization on atheistic communists.
Now Gates accuses the US Government (the Trump Administration?) of failing to protect US citizens.
On April 26, 2018, I discussed factual representations of biologically-based cause and effect that probably led to the death of Timothy J. Cunningham. I told a friend that Cunningham’s publication record clearly reveals his ability to link viruses to the failed differentiation of all cell types in all living genera.
See his publications on

1)”Racial Disparities in Age-Specific Mortality”
2) “Sex-specific relationships between adverse childhood experiences”
3) “Associations between antioxidants and all-cause mortality”
and
4) “Health and Safety Issues for Travelers”

What Bill Gates Fears Most may be the revelations of facts about vaccines. Gates seems to be still promoting the live (or dead) virus-containing vaccines that have failed to protect anyone since the time they were supposed to start protecting us all.
Is he aware that An error made in 1925 led to a crisis in modern science?
The error replaced the creation of energy with models of statistical significance as if the answer to the question “What is Life?” was akin to computers that automagically emerged with the energy to run themselves.
See also: Arrowsmith (1925). If Bill Gates had studied US history, he might have learned that the 1925 Scopes Trial in Dayton, Tennessee predicted that teaching neo-Darwinian evolution would cause the next pandemic.
Instead see: Gates Foundation launches $12M Grand Challenge for universal flu vaccine, as Bill Gates urges world to prepare for war on pandemics
When Europeans “invaded” the Americas, indigenous human populations were decimated by the virus-driven degradation of their messenger RNA. Few American Indians had the amino acid substitution that protected them from the virus-driven pathology manifested in the deep sea. The virus-driven pathology has been linked to all physical and mental diseases/disorders on Earth via the 1918 Spanish influenza pandemic.
For comparison, everything known to all serious scientists about quantized energy-dependent RNA-mediated cell type differentiation has been linked to biophysically constrained viral latency.
See: Virus-mediated archaeal hecatomb in the deep seafloor and Cytosis.
See for comparison: Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk
The V370A adaptation came from populations in what is now Central China, but dietary changes eliminated the need for the adaptation in the Americas, where indigenous populations had adapted to other viruses. When Europeans introduced the viruses to indigenous populations on other continents, the 6,000 year history of ecological adaptations in species from mice to humans became clear.
See: Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant
The EDAR variant is V370A, which is also known as The ectodysplasin receptor variant (EDARV370A) and as rs3827760, which is also known as 1540T/C, 370A or Val370Ala. It is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2. The fact that one food energy-dependent variant in one SNP was linked from the creation of a receptor to biophysically constrained RNA-mediated cell type differentiation in species from mice to humans proved that environmental selection links quantized energy-dependent changes in the microRNA/messenger RNA balance from the creation of sunlight to viral latency in all living genera.
See for comparison: Here Are Michelle Wolf’s Boldest Moments At The White House Correspondents’ Dinner
See also the bold moves made by scientific creationists in South Korea, who forced the denuclearization of North Korea (in the same week as the “dinner”) with prior publication of two articles that link viruses to the decimation of populations of atheistic Communists.
Whether or not the US, and/or if South Korea invades, they could decimate the populations of atheists without firing more than one shot to deliver a payload of virus-modified yeasts. The lives of well-nourished troops could be saved for the take-over/occupation.
See:
1) A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses 4/13/18

Several amino acid mutations were identified in PB2, PB1, PA, BM2, and/or NS1 protein coding regions, and one concurrent lysine (K)-to-arginine (R) mutation in PA residue 338 (PA K338R) was found in both maVc_BR60 and maYm_WI01 viruses.

2) Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/18/18

…17-24 amino acid changes, specifically A87T, D96N, S213D, and S242N substitutions in G2 epitopes, were observed.

See also: South Korea: Kim Seeks U.S. Guarantee Against Invasion

If the only thing atheistic Communists want is to not be invaded, they probably know that vaccines and nuclear weapons cannot protect them from the decimation that could be caused by a single amino acid substitution in a virus.

Why tempt our Creator to show them the error of their ways, when atheistic Communists do not believe in Him? Ask also, “Who killed Timothy J. Cunningham?” — and/or anyone else who is killed or goes missing during the transition to Global Peace.
See also:  [evol-psych] Sorry but Yahoo! groups have blocked all my news items — Robert Karl Stonjek 4/30/18
Wait for this to happen with the Human Ethology Yahoo group, where you can still find the atheistic pseudoscientific nonsense touted by the moderator, Jay R. Feierman.
See for example:
Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.
See also: I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that “Random mutations are the substrate upon which directional natural selection acts” is a correct and true statement.
See for comparison: Tracking niche variation over millennial timescales in sympatric killer whale lineages

  1. Ecological variation is the raw material by which natural selection can drive evolutionary divergence [1–4].
  2. The differences in amino acid composition among different tissues can lead to large differences in trophic discrimination [38].

Many evolutionary theorists and Big Bang cosmologists are among the hate-mongers who would rather combat Christianity than make any efforts towards Combating Evolution to Fight Disease.

Watering Young Plant - Vintage Effect

Environmental selection is natural selection (4)

Conclusion: Only biologically uninformed science idiots still believe in the pseudoscientific nonsense of neo-Darwinian evolution.
VISUALIZING APOPTOSIS AS IT HAPPENS

Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms.

Biologically uninformed theorists have claimed the conserved molecular mechanisms of energy-dependent apoptosis in multicelluar organisms arose after energy emerged. Aberrations in this form of energy-dependent programmed cell death have been linked from the virus-driven theft of quantized energy to all pathology. That helps to explain why biologically uninformed science idiots continue to link emergence to the evolution of all biodiversity but serious scientists present experimental evidence of highly regulated apoptosis.
Every level of biological organization has now linked the anti-entropic virucidal energy of sunlight to the proton motive force from apoptosis to all biodiversity via what is known about biophysically constrained viral latency.
For more evidence of obfuscation that theorists have used in their attempts to support their pseudoscientific nonsense “Download this eBook from The Scientist and Biotium to find out more about”

– The intrinsic and extrinsic apoptosis pathways
– The biochemical and morphological stages of apoptosis
– Apoptosis signs and signals
– Nuclear events during apoptosis

Quantized energy-dependent changes link the extrinsic pathway to the instrinsic pathway via changes in the microRNA/messenger RNA balance, which links the physiology of pheromone-controlled reproduction to biophysically constrained RNA-mediated fixation of amino acid substitutions and ecological adaptations in the context of viral latency.
For links to what is known about the role of anti-entropic virucidal energy links the proton motive force from protection of the mitochondrial membrane to all biophysically constrained biodiversity, see:
Reappraising the human mitochondrial DNA recombination dogma
Substitute energy-dependent ecological adaptation each time you see others suggest that human mitochondrial DNA recombination evolved.
See also:  If you can’t explain something in simple terms, you don’t understand it

Sizing up his audience perfectly, Feynman said, “I’ll prepare a freshman lecture on it.” But he came back a few days later to say, “I couldn’t do it. I couldn’t reduce it to the freshman level. That means we don’t really understand it.”

He died in 1988. Anyone who continues to claim that we still do not understand the links from quantum physics to quantum souls exemplifies human idiocy. See: Food energy
Only biologically uninformed science idiots still believe in the pseudoscientific nonsense of neo-Darwinian evolution.

(E) KEGG analysis of the common up- and downregulated mRNAs in NDV infection. The left panel shows the KEGG enrichment analysis of each of the top 20 significant differences in the upregulated mRNAs, and the right panel shows the KEGG enrichment analysis of each of the top 20 significant differences in the downregulated mRNAs.

The eternal significance of microRNAs (6)

Accurate representations of how mutations are linked to the ecological adaptations in viruses that kill us are required to end the stranglehold that pseudoscientists have held on medical research. The pseudoscientists and other theorists make claims about mutation-driven evolution or natural selection and evolution as if the effect of virus-driven energy theft was beneficial to species that have somehow evolved from other species.
Neo-Darwinian theories will cause the death of us all. But first they will kill all the chickens.
Common microRNA-mRNA Interactions in Different Newcastle Disease Virus-Infected Chicken Embryonic Visceral Tissues
figure 3 E (above) includes biosynthesis of amino acids but a word search for “amino acid” turns up nothing.

(E) KEGG analysis of the common up- and downregulated mRNAs in NDV infection. The left panel shows the KEGG enrichment analysis of each of the top 20 significant differences in the upregulated mRNAs, and the right panel shows the KEGG enrichment analysis of each of the top 20 significant differences in the downregulated mRNAs.

The pathways for the biosynthesis of amino acids link microRNA biogenesis from energy-dependent changes in base pairs to amino acid substitutions that stabilize or destabilize the organized genomes in the context of everything that could be learned by playing the cell biology game “Cytosis.”
Ages 10+ can learn how to protect all organized genomes from viruses in the context of the food energy-dependent pheromone-controlled physiology of reproduction of humans, which biophysically constrains viral latency in species from microbes to humans.
One base pair change and one amino acid substitution (e.g., EDAR V370A) in a human host may be all that’s required to protect the organized genome from the virus-driven degradation of mRNA that has been linked to all pathology.
That means the virus-driven theft of quantized energy may link the change in the base pair to an amino acid substitution in the virus that stabilizes the virus. The 1918 Spanish flu was one example of what happens next. But no one knew why it happened until more recently.
See:  Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution (2013)

Koel et al. (p. 976) show that major antigenic change can be caused by single amino acid substitutions.

See also: A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses (2018)

…the PA K338R mutation may be a molecular determinant of IBV pathogenicity via modulating the viral polymerase function of IBVs.

Accurate representations of how mutations are linked to ecological adaptations in viruses are required to end the stranglehold that pseudoscientists have held on medical research. The pseudoscientists and other theorists make claims about mutation-driven evolution or natural selection and evolution as if the effect of virus-driven energy theft was beneficial to species that have somehow evolved from other species.
The most recent example of that nonsense may be the focus of several blog posts here.
See:  Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk

…we investigate whether the population occupying Beringia during the LGM represents another example of human adaptation to an extreme environment, this time adapting to very low UV exposure (Fig. 1). There are two lines of genetic evidence for this: variation in the fatty acid desaturase (FADS) gene cluster that modulates the manufacture of polyunsaturated fatty acids and variation in the ectodysplasin A receptor (EDAR) gene that influences ectodermally derived structures, such as teeth, hair, and mammary gland ductal branching. A study on selection on the FADS gene cluster in the ancestral population of Native Americans has been published previously (13), but, here, we shift the emphasis from phenotypic effects on older adults to focus on those that influence fertility via breast milk.

They link the food energy-dependent creation of microRNAs in all mammals from the physiology of reproduction to biophysically constrained viral latency via one base pair change an a single amino acid substitution, EDAR V370A. They refuse to acknowledge the facts that link the creation of the sun’s anti-entropic virucidal energy from the creation of microRNAs to viral latency in the mouse-to-human model, and fail to link what is known about what animals eat from the physiology of reproduction to the transgenerational epigenetic inheritance of healthy longevity and fertility.
See: The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression (2014)

The potential for sperm miRNA affecting zygote development has recently been reported in the literature [18] and has interesting implications for the use of sperm miRNA profiles as indicators of potential male fertility.

See also: Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition (2016)

The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease.

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The chicken-livered (timid; fearful; cowardly) theorists who refuse to admit that their ridiculous theories have led to the unnecessary suffering and premature death of millions to billions of people and other mammals, have brought us all to the brink of extinction.
Does any intelligent person think that humans will evolve another protective variant allele like the EDAR V370A variant before humanity — as we know it know – ceases to exist?
Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk

The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to have occurred circa 20,000 y ago.

 
 
 
 
 
 

Plenty of Room at the Bottom

Environmental selection is natural selection (2)

I believe that if you put enough biologically uniformed theorists in the same room, they will invent more theories to support the pseudoscientific nonsense they have touted in the past. See for example:

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk

Acknowledgments

The synthesis presented here is a product of the American Association for the Advancement of Science’s 2017 annual meeting, as the ideas came together in the session entitled “Beringia and the Dispersal of Modern Humans to the Americas.”
 

Every aspect of every level of biophysically constrained food energy-dependent biologically-based cause and effect is placed back into the context of a ridiculous theory of human migration and evolution. The theory accurately attests to the link from one food energy-dependent base pair change to biodiversity in human populations via fixation of one amino acid substitution. But then, something goes horribly wrong.

The theory requires the fixation of the amino acid substitution to automagically occur in the context of the sun’s anti-entropic virucidal energy. The theory fails to mention the fact that the physiology of pheromone-controlled reproduction and the microRNA-mediated creation of all cell types in all living genera is required.

See for comparison: Anything published since the time I learned about the importance of microRNAs during the 2012 Society for Neuroscience annual meeting in New Orleans, LA.

From 2000/10/15 to 2012/10/15 microRNA Items: 1 to 20 of 19910

From 2012/10/15 to 2018/04/26 microRNA Items: 1 to 20 of 53458

The number of biologically informed serious scientists who have linked the energy-dependent creation of microRNAs to biophysically constrained viral latency and all biodiversity via the pheromone-controlled physiology of reproduction in bacteria continues to rapidly increase.

This begs the question: When will biologically uninformed science idiots stop attending meetings that facilitate their attempts to invent more ridiculous theories?