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1) Does what organisms eat link food energy to RNA-directed DNA methylation and all healthy longevity via fixation of amino acid substitutions and transgenerational epigenetic inheritance in the context of the physiology of pheromone-controlled reproduction in species from microbes to humans?
2) Does the virus-driven theft of quantized energy link the loss of information from impaired methylation to all pathology?
The potential for sperm miRNA affecting zygote development has recently been reported in the literature  and has interesting implications for the use of sperm miRNA profiles as indicators of potential male fertility.