amino acid homeostasis

Carl Woese was wrong


Using ribosomal RNA sequence as an evolutionary measure, his laboratory provided a phylogenetically valid system of classification for prokaryotes; the revised classification of the archaebacteria was a product of these studies.  His research later focused on defining ancestral gene families, determining the evolution of cellular translation, and tracing the origin of the genetic code.

See for comparison: Nascent Proteome Remodeling following Homeostatic Scaling at Hippocampal Synapses


…although it has not been explicitly addressed here, it is obvious that the regulated degradation of proteins must also play a role in sculpting the proteome during homeostatic scaling. Indeed, we observed many proteins in the ubiquitin proteasome pathway that were regulated by scaling (Figure 3C; Table S3).

My comment: This refutes all the neo-Darwinian pseudoscientific nonsense that has ever been touted by biologically uninformed theorists. Energy-dependent protein biosynthesis and degradation links feedback loops from odor and pheromones to the physiology of reproduction in all living genera.

Virus-driven energy theft links the degradation of messenger RNA to all pathology. All pathology includes the transgenerational epigenetic inheritance of Zika virus pathology.

It is directly comparable to the virus-driven pathology that differentiates archaea from ecologically adapted bacteria and eukaryotes.

Simply put, Carl Woese was wrong. There are not 3 different forms of life, and no form evolved from any other form. There is only ecological variation and energy-dependent ecological adaptation for comparison to virus-driven energy theft and all pathology.

See also:  Neurons adjust their proteins during homeostatic scaling

Changes in the synthesis of cellular proteins lie at the heart of all adaptations that cells undergo.

My comment: Autophagy links the energy-dependent changes in protein biosynthesis and degradation from natural selection for codon optimality to the RNA-mediated amino acid substitutions that differentiate all cell types in all living genera in the context of the physiology of reproduction.
What is it that pseudoscientists, theorists, and atheists do not understand about that fact?

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