Epigenetics and autophagy vs mutations and evolution (7) November 12, 2016 by James Kohl with no comment AdaptationsAlternative SplicingsAutophagyDiseases & DisordersEcologyLight EnergyModel OrganismsPhysicsRNA DirectedRNA-directed DNA methylationVariations RNA interference (RNAi) fails to protect all cell types from virus-driven energy theft. The effect on some cell types cannot be controlled. That’s because nutrient energy-dependent endogenosymbiosis and the pheromones-controlled physiology of reproduction protect the organized genomes of species from microbes to humans. Billions of waster dollars have been spent with no end to the waste in sight — until the Trump administration stops it. As that begins to happen, see: tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence (open access) Excerpt: Codon re-engineering of dosR exaggerates hypoxia-induced changes in codon-biased DosR translation, with altered dosR expression revealing unanticipated effects on bacterial survival during hypoxia. These results reveal a coordinated system of tRNA modifications and translation of codon-biased transcripts that enhance expression of stress response proteins in mycobacteria. My comment: Natural selection for energy-dependent biophysically constrained RNA-mediated protein folding chemistry is the coordinated system that links autophagy to supercoiled DNA. Pseudoscientists, atheists, and the YEC admins on “The Battlefield” FB group do not want anyone to know that energy-dependent pheromone-controlled metabolic networks and genetic networks clearly exemplify that fact. Supercoiled DNA prevents virus-driven energy theft, which links mutations to all pathology via the conserved molecular mechanisms of RNA-mediated amino acid substitutions and cell type differentiation. That fact has been known to all serious scientists for several decades. Instead of helping others learn about the facts, some people would like you to believe that a newly discovered genetic code controls the future of energy-dependent healthy longevity in species from microbes to humans. If it’s a new code, their ignorance can be excused. If it’s new, they could not be expected to know about it. But energy-dependent natural selection for energy-efficient codon optimalitly is nothing new. It’s the survival mechanism that prevents virus-driven energy theft from causing all pathology in all living genera. It’s called autophagy. Reported as: Newly discovered genetic code controls bacterial survival during infections Those amino acids are delivered to the ribosome by tRNA. Like other types of RNA, tRNA consists of a sequence of four main ribonucleosides—A, G, C, and U. (U in RNA substitutes for the T found in DNA.) Each tRNA molecule has an anticodon that matches an mRNA codon, ensuring that the correct amino acid is inserted into the protein sequence. However, many amino acids can be encoded by more than one codon. For example, the amino acid threonine can be encoded by ACU, ACC, ACA, or ACG. In total, the genetic code has 61 codons that correspond to only 20 amino acids. My comment: Bacterial survival is nutrient energy-dependent and pheromone-controlled in the context of metabolic networks and genetic networks that clearly link chemotaxis and phototaxis to the physiology of reproduction in species from microbes to humans. Energy-dependent alternative splicings link the microRNA/messenger RNA balance to all morphological and behavioral phenotypes in all living genera via Darwin’s “conditions of life” and everything known about energy-dependent cell type differentiation or virus-driven energy theft, which links mutations to all pathology. See for comparison: Panayiotis Stavrou to Religion: Science & Psychology PLEASE SOMEONE TELL ME THIS IS A JOKE… A POE, SOME BANTER…SOMETHING??? American politician and former member of the United States House of Representatives made this ridiculous observation on television. 6.57 video 6.37 video My comment: From the dawn of Creation, this energy-dependent coordinated system of codon usage (autophagy) has linked the sun’s anti-entropic virucidal energy to biophysically constrained protein folding chemistry via RNA-mediated amino acid substitutions in supercoiled DNA, which protects all organized genomes from virus-driven energy theft and all pathology in all living genera. That fact may play a role in linking claims like the one Michele Bachmann and others have made about the importance of including consideration for God’s ongoing direction in the life of all creatures that He created. Atheists will always think the claims of theists are unreasonable, which may sometimes be true. However, atheists cannot support their claims with experimental evidence linked to biologically-based cause and effect. That has always been true. The atheistic alternative is to credit emergence and evolution via mutations to all pathology without acknowledgement of any anti-entropic force such as sunlight, which is directly and indirectly linked to all healthy longevity in all living genera via RNA-mediated DNA repair. For comparison, there is no model of biologically-based cause and effect that suggests healthy longevity emerged and evolved from anything. The innate immune system has always been considered the link from the epigenetic landscape to the physical landscape of supercoiled DNA by all serious scientists. Previous Post Epigenetics and autophagy vs mutations and evolution (6) Next Post Epigenetically effected energy-dependent fluorescence