“Tobacco mosaic virus (TMV) is a positive-sense single stranded RNA virus that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as “mosaic”-like mottling and discoloration on the leaves (hence the name). TMV was the first virus ever to be discovered. Although it was known from the late 19th century that an infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus.”
My comment: In 1933 Thomas Hunt Morgan won the Nobel Prize in Physiology or Medicine for linking chromosomal inheritance to all biodiversity and Yoshinori Ohsumi won the 2016 prize for linking autophagy to all biodiversity.
See also: “Autophagy is a self-degradative process that is important for balancing sources of energy at critical times in development and in response to nutrient stress. Autophagy also plays a housekeeping role in removing misfolded or aggregated proteins, clearing damaged organelles, such as mitochondria, endoplasmic reticulum and peroxisomes, as well as eliminating intracellular pathogens.”
My comment: The intracelluar pathogens include human endogenous retroviruses that must be biophysically constrained by energy-dependent changes in organized genomes that link angstroms to ecosystems in all living genera via the physiology of reproduction. All serious scientists know that, and all pseudoscientists seem to be completely unaware that their ridiculous theories started to be removed from consideration by serious scientists more than 80 years ago.
…the closer we look at DNA, RNA, genes, and non-gene mechanisms, the less we find random change in a dominant role.