See also: Hydrogen-Atom Transfer in DNA Base Pairs
Ultrafast vibrational dynamics of the DNA backbone at different hydration levels mapped by two-dimensional infrared spectroscopy
…the hydration level is substantially below a bulk water environment existing under physiological conditions. To get insight into this biologically most relevant scenario, future work will address the behavior of longer DNA helices and RNA with sodium counterions, embedded in bulk liquid water. Such work will also help to assess the role of long-range electric interactions and the underlying dynamic potentials beyond the DNA-water interface.
In a biological system, the ratio of water-to-non-water molecules, known as the hydration level, influences both the arrangement of biomolecules and the strength of the electric interactions that occur between biomolecules, free ions, and functional groups, which are groups of atoms within molecules that strongly influence the molecules’ chemical properties.