Success in antimalarial therapy depends on how clever scientists are in using combinations of drugs.
Dr. Omura played down his accomplishments, saying, “I merely borrowed the power of microbes.”
My comment: These two excerpts appear within the context of three paragraphs that clearly link RNA-mediated cell type differentiation in species from microbes to humans. The context attests to what at first may appear to be a political agenda inserted into Western medical practice.
The first appearance of that Westernized political agenda was never removed during my career as a medical laboratory scientist.
“…malaria parasites have developed resistance against Artemisinin in Asia — but not Africa…”
My comment: In species from microbes to humans, RNA-mediated cell type differentiation links nutrient-dependent base pair changes to biodiversity via single amino acid substitutions in the context of the physiology of reproduction, which leads to fixation of beneficial substitutions that stabilize organized genomes.
For example, Dobzhansky (1973) claimed that “…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.”
Recent reports in “Science Magazine” linked this RNA-mediated event from the nutrient-dependent physiology of reproduction in bacteria to humans via what is known about thermodynamic cycles of protein biosynthesis and degradation.
The cycles of cold and heat prevent viral replication which ultimately occurs when viruses try to ecologically adapt to a new cell type via a single amino acid substitution. See: Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution
The major antigenic changes of the influenza virus are primarily caused by a single amino acid near the receptor binding site.
Moving forward: These Nobel Laureates have helped to remove any further consideration of mutations and evolution in all living genera by focusing individually and collectively on the conserved molecular mechanisms that link physics, chemistry, and molecular epigenetics to disease prevention and treatment.
Clearly, they are among others who are “Combating Evolution to Fight Disease” But, in this case, they have been doing that since the 60’s and 70’s.
See also: Three share Nobel medicine prize for new tools to kill parasites (Update)
Working in the 1970s, Omura isolated new strains of Streptomyces bacteria and cultured them so that they could be analyzed for their impact against harmful microorganisms, the Nobel committee said.
See also: The Man Who Bottled Evolution and Mutation-Driven Evolution
See for comparison: Antiparasite Drug Developers Win Nobel
My comment: Reports or books that link theories about mutations and evolution to antibiotic resistance and/or all biodiversity should already have been corrected. Two generations of researchers need not have been taught to believe in pseudoscientific nonsense. They might have learned the difference between a mutation and a nutrient-dependent RNA-mediated amino acid substitution.
Instead, de Vries 1904 definition of mutation is still used by neo-Darwinian theorists who don’t know that viruses steal energy that cells require to ensure proper protein folding.
Viruses do not cause de Vries “energy jumps.” The energy jumps are nutrient-dependent. They enable the innate immune system to “jump” to a higher level of control in the context of the physiology of reproduction that transgenerationally protects organized genomes from virus-driven genomic entropy. Simply put, the energy jumps link RNA-mediated events to DNA repair and healthy longevity via protection against virus-driven entropic elasticity that would otherwise lead to genomic entropy much faster than it ultimately does.