Summary: Recent findings suggest that polyphenols display the ability to reverse adverse epigenetic regulation involved in pathological conditions, such as obesity, metabolic disorder, cardiovascular and neurodegenerative diseases, and various forms of cancer.
That suggests the ignorance of pseudoscientists who fail to link pattern recognition from the food that organisms eat to the pheromone-controlled physiology of reproduction via microRNAs is the cause of all pathology.
After just three weeks of development, worker bees emerge from their brood cells fully formed, flying out to begin supporting their hive. In a stunning high-definition time-lapse video, the US photographer Anand Varma follows the bee’s stages of development from egg to larvae to pupa to worker bee, with a sprightly score to match the insects’ rather startling journey into being.
From Fertilization to Adult Sexual Behavior links the 21 days of bee development to food energy-dependent pheromone-controlled RNA-mediated biodiversity in all living genera via the molecular mechanisms detailed in Nutrient-dependent/pheromone-controlled adaptive evolution: a model.
This model details how chemical ecology drives adaptive evolution via: (1) ecological niche construction, (2) social niche construction, (3) neurogenic niche construction, and (4) socio-cognitive niche construction. This model exemplifies the epigenetic effects of olfactory/pheromonal conditioning, which alters genetically predisposed, nutrient-dependent, hormone-driven mammalian behavior and choices for pheromones that control reproduction…
The model is a refutation of neo-Darwinian pseudoscientific nonsense that linked atoms to ecosystems in Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems via food energy-dependent changes in microRNAs.
This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA / messenger RNA balance and chromosomal rearrangements. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent protein folding; experience-dependent receptor-mediated behaviors, and organism-level thermoregulation in ever-changing ecological niches and social niches. Nutrient-dependent pheromone-controlled ecological, social, neurogenic and socio-cognitive niche construction are manifested in increasing organismal complexity in species from microbes to man.
A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
The energy-dependent innate ability to fend off attacking viruses links changes in chirality to autophagy and supercoiled DNA, which links the physiology of reproduction to the viral latency that protects all organisms from the virus-driven degradation of messenger RNA. The virus-driven degradation of messenger RNA is linked from mutations to all pathology by all serious scientists.
For example, see:Two new studies offer insights into gastrointestinal dysfunction in Parkinson’s patients
The GI distress has repeatedly been linked from the virus-driven degradation of messenger RNA in gut bacteria to all pathology via links from quantum physics to supercoiled DNA, which protects all organized genomes from virus-driven pathology. You need only look up “microRNA” in a search of the PubMed database to learn what theorists are not telling you about biologically-based cause and effect.
See also: Cell senescence is regulated by innate DNA sensing
The innate immune cells use a host of pattern recognition receptors to sense and identify foreign parts of an invading pathogen, such as the DNA of a virus. DNA-sensing is accomplished through a two-receptor system comprising an enzyme called cGAS and an adaptor molecule called STING. Once activated, the cGAS-STING pathway triggers the production of inflammatory proteins that help fight off the pathogen.
The energy-dependent de novo creation of G protein-coupled receptors links the virus-driven degradation of messenger RNA to all pathology. See: Olfaction Warps Visual Time Perception
For an example of someone who has failed to link pattern recognition to top-down causation and all biophysically-constrained biologically based-cause and effect, see: Discovering Hidden Temporal Patterns in Behavior and Interaction: T-Pattern Detection and Analysis with THEME™
Magnus S. Magnusson, who I sometimes describe as an atheistic hate-monger, claims that my model and all my comments to his FB page are:
“Ridiculously irrelevant. I may not be intelligent, but I give keynotes at international conferences in proteomics and mass spectroscopy and in a few weeks in nanotechnology. However, I have mostly worked on the biology of behavior and neuroscience especially regarding neuronal interactions in the brain with the University if Cambridge, UK.”
He won’t answer any questions about the role of energy-dependent receptor-mediated interactions that link the de novo creation of the receptors to all biologically-based cause and effect. He does not seem to grasp the fact that viruses steal the quantized energy that links the de novo creation of the receptors to healthy longevity, which may be why he cannot link virus-driven energy theft to all pathology.
See for comparison: Evolutionary processes shaping diversity across the Homo lineage
These results show that genetic drift, and, likely, small population sizes were important factors shaping the evolution of Homo and many of its novel traits, but that selection played an essential role in driving adaptation to new contexts.
When all else fails to convince any serious scientist, pseudoscientists will still have their “evolutionary processes.” For comparison, serious scientists will continue to link what organisms eat to the physiology of their pheromone-controlled biodiversity and use microRNA therapy to effectively treat or cure all pathology.
Study shows mango consumption has positive impact on inflammatory bowel disease
Facts about food consumption and ecological adaptations include links to the control of virus-driven messenger RNA degradation and control of inflammatory bowel disease. The facts make sense in the context of this model. Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems
See also: Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs
See also: Dietary polyphenols and chromatin remodeling
Recent findings suggest that polyphenols display the ability to reverse adverse epigenetic regulation involved in pathological conditions, such as obesity, metabolic disorder, cardiovascular and neurodegenerative diseases, and various forms of cancer.
See also: This brief exchange with Jay R. Feierman
James V. Kohl: “Evolution by natural selection cannot be the outcome if something is not first selected. Selection is always for nutrients. It is as simple as that.”
Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.
Jay R. Feierman: I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that “Random mutations are the substrate upon which directional natural selection acts” is a correct and true statement.
See for comparison: New Research Shocks Scientists: Human Emotion Physically Shapes Reality!
In the presence of negative emotions the DNA tightened. In the presence of positive emotions the coils of the DNA relaxed.
The scientists concluded that “Human emotion produces effects which defy conventional laws of physics.”
The DNA was placed in a different room in the same building. Both the donor and his DNA were monitored and as the donor exhibited emotional peaks or valleys (measured by electrical responses), the DNA exhibited the IDENTICAL RESPONSES AT THE EXACT SAME TIME.
The third experiment proved something pretty shocking!
Scientists observed the effect of DNA on our physical world.
Light photons, which make up the world around us, were observed inside a vacuum. Their natural locations were completely random.
Human DNA was then inserted into the vacuum. Shockingly the photons were no longer acting random. They precisely followed the geometry of the DNA.
Scientists who were studying this, described the photons behaving “surprisingly and counter-intuitively”. They went on to say that “We are forced to accept the possibility of some new field of energy!”
They concluded that human DNA literally shape the behavior of light photons that make up the world around us!
Until you link quantum physics to quantum souls via olfaction, you may not understand any claim about light-induced energy-dependent changes in the endogenous substrate of all cell types that links the creation of RNA from top-down causation to every aspect of energy-dependent RNA-mediated cell type differentiation.
Human DNA does not shape the behavior of light photons. The speed of light on contact with water links the anti-entropic virucidal energy of sunlight to the de novo creation of amino acids and supercoiled DNA via feedback loops. The experiments linked the feedback loops from behavior to changes in DNA, and biologically uninformed science idiots claimed that DNA shapes the behavior of light photons.
The idiots (people who have no professional expertise in any scientific discipline) claim that “…we are connected to our DNA beyond space and time.”
See for comparison: Olfaction Warps Visual Time Perception
At this level of examination, the researchers link the sense of smell in bacteria from quorum-sensing to the physiology of pheromone-controlled reproduction in all living genera via the honeybee model organism and our visual perception of energy and mass in the context of the space-time continuum via feedback loops. Nothing happens to us that is outside our ability to unconsciously perceive energy and mass. No magic exists in the context of facts like this: Feedback loops link odor and pheromone signaling with reproduction
See also: Roger Penrose On Why Consciousness Does Not Compute
…I asked him if he thinks there’s any inherent meaning in the universe. His answer surprised me. “Somehow, our consciousness is the reason the universe is here.” So does he think there’s intelligent life—or consciousness—somewhere else in the cosmos? “Yes, but it may be extremely rare.” But if consciousness is the point of this whole shebang, wouldn’t you expect to find some evidence of it beyond Earth? “Well, I’m not so sure our own universe is that favorably disposed toward consciousness,” he said. “You could imagine a universe with a lot more consciousness that’s peppered all over the place. Why aren’t we in one of those rather than this one where it seems to be a rather uncommon activity?
“So, yes, we want to see the purpose of it. I don’t know. Maybe it’s attributing the wrong word. Purpose—what does that mean?” He chuckled.
Evolution–who thinks that the purpose of life can be placed into the context of ridiculous theories about evolutionary processes.
See for comparison: Structural diversity of supercoiled DNA (and this parody). See also: Chemists Know and m1A and m1G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs