Summary: Christ’s lab showed that in vivo formation of I-motif structures is pH dependent and helped to put the “fear of God” into atheistic communists.
Christ’s lab showed that in vivo formation of I-motif structures is pH dependent. Clearly, the potential of hydrogen (pH) and pH-dependent cell cycles link the quantized energy of virucidal sunlight to protection from the degradation of messenger RNA that links mutations to all pathology.
In that context, denuclearization has been forced on North Korea and other communist countries by scientific creationists in South Korea. The creationists have indirectly revealed that they could decimate human populations in China via the creation of a virus with one base pair change linked to one amino acid substitution.
See also: Virus-mediated archaeal hecatomb in the deep seafloor
We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.
Until recently, the pseudoscientific nonsense about vaccines that could protect human populations from the forthcoming viral apocalypse was tightly linked from communism to atheism. For comparison, Christ’s lab appears to have put the fear of God into its proper context; the 1918 Spanish flu.
Previously reported as: Structural diversity of supercoiled DNA (2015) and parodied in:
Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy.
The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent fixed amino acid substitutions to the Precision Medicine Initiative via genome wide inferences of natural selection.
This detailed representation of energy-dependent natural selection for codon optimality links biologically- based cause and effect from G protein-coupled receptors to RNA-mediated amino acid substitutions and the functional structure of supercoiled DNA. Energy-dependent polycombic ecological adaptations are manifested in supercoiled DNA.
Chromosomal inheritance links the adaptations from morphological phenotypes to healthy longevity via behavioral phenotypes. For contrast, virus-driven energy theft is the link from messenger RNA degradation to negative supercoiling, constraint breaking mutations, and hecatombic evolution.
The viral hecatomb links transgenerational epigenetic inheritance from archaea to Zika virus-damaged DNA, which typically is repaired by endogenous RNA interference and fixation of RNA-mediated amino acid substitutions in organized genomes.
Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent fixed amino acid substitutions to the Precision Medicine Initiative via genome wide inferences of natural selection.
This detailed representation of energy-dependent natural selection for codon optimality links biologically- based cause and effect from G protein-coupled receptors to RNA-mediated amino acid substitutions and the functional structure of supercoiled DNA. Energy-dependent polycombic ecological adaptations are manifested in supercoiled DNA. Chromosomal inheritance links the adaptations from morphological phenotypes to healthy longevity via behavioral phenotypes. For contrast, virus-driven energy theft is the link from messenger RNA degradation to negative supercoiling, constraint breaking mutations, and hecatombic evolution. The viral hecatomb links transgenerational epigenetic inheritance from archaea to Zika virus-damaged DNA, which typically is repaired by endogenous RNA interference and fixation of RNA-mediated amino acid substitutions in organized genomes.
See for comparison: Church SpeaksA Conversation WithGeorge Church (February 14, 2018)
[Arctic grass and] cyanobacteria, on the other hand, they fix [carbon]. Cyanobacteria turn carbon dioxide, a global warming gas, into carbohydrates and other carbon-containing polymers, which sequester the carbon so that they’re no longer global warming gases. They turn it into their own bodies. They do this on such a big scale that about 15 percent of the carbon dioxide in the atmosphere is fixed every year by these cyanobacteria, which is roughly the amount that we’re off from the pre-industrial era. If all of the material that they fix didn’t turn back into carbon dioxide, we’d have solved the global warming problem in a year or two. The reality, however, is that almost as soon as they divide and make baby bacteria, phages break them open, spilling their guts, and they start turning into carbon dioxide. Then all the other things around them start chomping on the bits left over from the phages.
The anti-entropic virucidal quantized energy of sunlight links the creation of ATP to the creation of microRNAs and changes in the energy-dependent microRNA/messenger RNA balance, which link what organisms eat to RNA-mediated fixation of amino acid substitutions that differentiate all cell types in all individuals of all living genera. Simply put, sunlight, food energy, and pheromones biophysically constrain the DNA damage that is done by phages.
Release of the cell biology game “Cytosis” and the forthcoming conference Evolution – Genetic Novelty/Genomic Variations by RNA Networks and Viruses (4 – 8 July 2018 Salzburg – Austria) have forced George Church and others like him to begin telling the scientific truth about how the virus-driven theft of quantized energy is either biophysically constrained, or linked from the virus-driven degradation of messenger RNA to mutations and all pathology.
Chantal Abergel >
Aix-Marseille University, Centre National de la Recherche Scientifique, Information Génomique & Structurale, Marseille, France Gustavo Caetano Anolles >
Department of Crop Sciences, Evolutionary Bioinformatics Laboratory, University of Illinois at Urbana-Champaign Urbana, USA.
Marlene Belfort >
Department of Biological Sciences and RNA Institute, University at Albany, New York, USA Felix Broecker > Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
Department of Chemistry & Biochemistry, University of California, Santa Barbara, USA Julian Chen >
Department of Chemistry and Biochemistry, Arizona State University, Tempe, USA Jean-Michel Claverie >
Centre National de la Recherche Scientifique & Aix-Marseille University, Marseille, France Bryan Cullen >
Department of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, USA
Valerian Dolja >
Department of Botany and Plant Pathology, Oregon State University, Corvallis, USA Cedric Feschotte >
Department of Human Genetics, University of Utah, School of Medicine, Salt Lake City, USA Matthias Fischer >
Max Planck Institute for Medical Research, Department of Biomolecular Mechanisms, Heidelberg, Germany
David Gilmer >
Institut de biologie moléculaire des plantes, Integrative virology, Strasbourg, France
Reynald Gillet > Université de Rennes 1, Translation and Folding Team, Rennes cedex, France Institut Universitaire de France Jordi Gomez >
Instituto de Parasitología y Biomedicina ‘López-Neyra’ (CSIC), Granada, Spain
Matti Jalasvuori >
Centre of Excellence in Biological Interactions, Department of Biological and Environmental Science, University of Jyväskylä, Finland I.King Jordan > School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA Eugene Koonin >
National Center for Biotechnology Information, National Library of Medicine, Bethesda, USA. Dusan Kordis >
Department of Molecular and Biomedical Sciences, Josef Stefan Institute, Ljubljana, Slovenia
Mart Krupovic >
Unit BMGE, Department of Microbiology, Institut Pasteur, Paris, France Erez Levanon >
Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel German Martinez >
Dept. of Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden John Mattick >
Garvan Institute of Medical Research, Darlinghurst, Australia Jeff Miller >
California NanoSystems Institute, University of California, Los Angeles, USA
Karin Moelling >
Max Planck Institute for molecular Genetics, Berlin, Germany Sabine Müller >
Universität Greifswald, Institut für Biochemie , Greifswald , Germany Ulrich Müller >
Department of Chemistry & Biochemistry, University of California, San Diego, USA Mariusz Nowacki >
Institute of Cell Biology, University of Bern, Baltzerstrasse 4, 3012 Bern, Switzerland David Prangishvili >
Department of Microbiology, BMGE, Institut Pasteur, Paris, France Lennart Randau >
Max Planck Institute for Terrestrial Microbiology, Marburg, Germany Forest Rohwer >
Department of Biology, San Diego State University, San Diego, CA, USA Corrado Spadafora >
Institute of Translational Pharmacology, CNR, Rome, Italy James Shapiro >
Department of Biochemistry and Molecular Biology , University of Chicago , IL , USA Jason Shepherd >
Biochemistry and Ophthalmology & Visual SciencesUniversity of Utah, School of Medicine Salt Lake City, USA Ravindra Singh >
Department of Biomedical Sciences, Iowa State University, Ames, USA Keizo Tomonaga >
Laboratory of RNA Viruses, Department of Virus Research, Institute for Frontier Life and Medical Sciences, Kyoto University, Japan Peter Unrau >
Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada Luis P. Villarreal >
Center for Virus Research, University of California, Irvine, Irvine, CA, USA Andreas Werner >
RNA biology group, Institute for Cell and Molecular Biosciences, Newcastle University, UK Eric Westhof >
Architecture and Reactivity of RNA, Institute of Molecular and Cellular Biology of the CNRS, University of Strasbourg, France Bojan Zagrovic >
Department of Structural and Computational Biology, Max F. Perutz Laboratories, Vienna, Austria
Steven Zimmerly >
Department of Biological Sciences, University of Calgary, Calgary, Canada
Linda Buck, Ben Feringa, Michael Gazzaniga, Christof Koch, Nick Lane and Svante Paabo are among the presenters who will almost undoubtedly discuss some or all of my claims.
Prepare to ask questions or intelligently discuss accurate representations of top-down causation by watching this:
MicroRNA present in mature sperm appears to not only be left over from spermatogenic processes, but may actually serve important regulatory roles in fertilization and early developmental processes. Further, our results indicate the possibility that environmental changes may impact the expression of specific miRNA.
We conclude that the enzymes involved took these alternatives by chance in independent populations that had already evolved distinct ion pumps. Our model offers a quantitatively robust explanation for why membrane bioenergetics are universal, yet ion pumps and phospholipid membranes arose later and independently in separate populations. Our findings elucidate the paradox that archaea and bacteria share DNA transcription, ribosomal translation, and ATP synthase, yet differ in equally fundamental traits that depend on the membrane, including DNA replication.
The microRNA-mediated creation of enzymes is quantized energy-dependent and biophysically constrained by phosphorylation in the context of food energy and the transgenerational epigenetic inheritance of all morphological and behavioral phenotypes in species from bacteria to primates. Membrane divergence in archaea occurs via the virus-driven degradation of messenger RNA, which links the loss of quantized energy from mutations to all pathology. The degradation of the cell membrane links archaea to L-forms, the last remnant of the life of a cell. See: The Inner Life of the Cell (video)
See also: Virus-mediated archaeal hecatomb in the deep seafloor (2016)
We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.
So far as I know, none of the people who are presenting at “The Future of Biology” meeting have linked Schroedinger’s claims from the past to what is known about the conserved molecular mechanisms of energy-dependent biophysically constrained RNA-mediated cell type differentiation in species from microbes to humans. Even if they are not evolutionary theorists, most have not linked the energy-dependent fixation of RNA-mediated amino acid substitutions to increasing organismal complexity and some have even reversed what is known about top-down causation. For example, Nick Lane, like Gunter P. Wagner have used mathematical models of correlations.
See: Pervasive correlated evolution in gene expression shapes cell and tissue type transcriptomes
They start with this admission”
A major challenge for interpreting this data is that cell type transcriptomes may not evolve independently…
They seem to think they can use statistics and interpretations to address the challenge of facts about increasing organismal complexity.
Our study provides a statistical method to measure and account for correlated gene expression evolution when interpreting comparative transcriptome data.
A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
During the month of January (2018), 2831 people learned from my twitter profile about the domains RNA-mediated.com and Autophagy.pro and some of them learned from more than 100,000 impressions how energy must be linked to RNA-mediated biophysically constrained viral latency by autophagy.
Jan 2018 Summary
Tweets
1,199
Tweet impressions
102,000
Profile visits
2,831
Mentions
71
New followers
29
Why do I have only 29 new followers? Are theorists really that scared? If so, how will they help to prevent the next viral apocalypse, if it has not already started before September, 2018?
See also:
If my claims about biophysically constrained energy-dependent RNA-mediated cell type differentiation are not discussed by Linda Buck, Ben Feringa, Michael Gazzaniga, Christof Koch, Nick Lane, and Svante Paabo others will have another example of what happens after a paradigm shift.
In the past nothing happened because serious scientists failed to acknowledge this fact: Feedback loops link odor and pheromone signaling with reproduction. The article was co-authored by LInda Buck. There is no mention of mutations or evolution and Linda Buck is scheduled to present what can best be described as a refutation of neo-Darwinian evolution.
Estradiol builds in the bloodstream until it reaches a concentration that causes a surge of the hypothalamic and pituitary hormones, including one called luteinizing hormone, which in turn trigger an ovary to release an egg.
Perhaps significantly, neuron-specific transcription regulation of neurosteroidogenic enzymes and subsequent neurosteroids production suggest clues to mechanisms that allow some persons to develop in accord with typical gonadal male-pattern or female-pattern hormones and have appropriate male-typical or female-typical physiques nonetheless have parameters of their sexual behavior profile quite opposite to their physical phenotype. For instance, it might be possible for local neurosteroid action in CNS loci specific for sexual orientation to operate independently of other hormonal production and separately from gross body morphology in general. This could, for instance, account for different manifestations of transsexualism and homosexuality.
The “gay agenda” served its proponents well as they attempted to bury the facts that link feedback loops from odors and pheromones to biophysically constrained viral latency.
Most sex researchers still live in fear that the biologically uninformed masses will learn that homosexual orientation is nothing more than another variation of what happens in the context of transgenerational epigenetic inheritance.
All serious scientists link food energy to the pheromone-controlled physiology of reproduction and autophagy, which protects all organized genomes from the virus-driven degradation of messenger RNA. The virus-driven degradation of messenger RNA links mutations to all pathology in species from microbes to humans.
If you try to make any aspect of pathology specific to any group of individuals in any human population, you challenge the totality of experimental evidence that links top-down causation to healthy longevity. You be forced to admit that you are not perfectly healthy, which means you are not qualified to judge the mental health or judge the physical health of others. The take home message is stop judging anyone based on your ignorance.
The across-species genetic conservation of intercellular and extracellular chemical communication enables unicellular and multicellular organisms to functionally distinguish between self and non-self. Non-self olfactory/pheromonal input from the social environment elicits a vertebrate neuroendocrine response. The organization and activation of this neuroendocrine response modulates the concurrent maturation of the mammalian neuroendocrine system, the reproductive system, and the central nervous system during the development of sexual preferences that may be expressed in sexual behavior. Psychophysiological mechanisms for the development of these sexual preferences include focus on unconscious affects that are detailed in reciprocal cause and effect relationships. Olfactory/pheromonal conditioning elicits neuroendocrine effects accompanied by unconscious affects on the development of sexual preferences. Integrating these unconscious affects extends to humans a developmental model of behavior that includes the development of male sexual preferences for other males.
Rarely do sex researchers address the ongoing philosophical debate between canonical neo-Darwinism and Biblical creation. Perhaps this is because any debate between scientific theory and religion arises from distinctly different domains of cognitive thought. Does the acceptance of Darwin’s theory represent the glorification of Science pitted against religion, or is it a means by which Science and religion might be integrated? Integration of Science and religion might be achieved by recognizing that the key components of this olfactory/pheromonal model appear to be as irreducibly complex as the basic tenets of evolution and the basic tenets of religion.
From an evolutionary perspective, highly conserved GnRH peptide ligand/receptor signaling mechanisms are the molecular biochemical mechanisms for sexual reproduction in all organisms. These signaling mechanisms also appear to play an integral role in the development of sexual preferences. From a religious perspective, these signaling mechanisms dictate that the creation of life, which begets life, also allows for the creation of diversified life through the same mechanisms. These mechanisms allow life to recognize the difference between self and non-self and to respond to this difference.
Perhaps the creation of diversified human life gave us the ability to recognize differences between our sexual behavior and the sexual behavior of others. Since all life does not beget diversified life, those who judge sexual preferences that do not seem to result in diversified life may be judging creation itself.
It is easy to understand how someone could judge a particular sexual preference, without thought. Unconscious affects that are manifest in the development of human sexual preferences are, by their nature, a part of diversified life that few people think about. What we think about human sexual preferences becomes less meaningful when we realize that most of sexual behavior is not what we cognitively think it should be. Indeed, the largest contributor to sexual preferences that are manifest in the sexual behavior of any species appears to be unconscious affect. This also appears to be the basis for diversified life.
The other startling thing about the new colossal fossil is its ancient age. At 55 to 60 million years old, it is nearly as old as the earliest penguin ancestors ever found. It would have lived during a geological period known as the Paleocene, just after the mass extinction 66 million years ago that wiped out non-bird dinosaurs.
The most startling thing about this ridiculous claim is that it cannot be linked from anything known to serious scientists about biophysically constrained viral latency to all biodiversity on Earth via the pheromone-controlled physiology of reproduction and chromosomal rearrangements in birds.
Two fixed differences among 597 amino acids drive a Val73Ile and Ala552Thr (valine to alanine) polymorphism in ZAL2m that distinguish its morphological and behavioral phenotype from ZAL2.
On 12/10/17, a long-term business partner called to tell me he was ending his efforts to sell human pheromone-enhanced fragrance products to those who understand how the products help to biophysically constrain viral latency in all mammals. QuEBS workshop has established itself as an outstanding stage to present the research in the intersection of physics, chemistry and biology. […] discussion of notable scientists and pioneers of Quantum Biology… established excitons in biology as the “must-talk-language” when describing the quantum effects in biological light-harvesting systems. Decades later, researchers reported on: Signatures of exciton condensation in a transition metal dichalcogenide. The mass media news representation is: Physicists excited by discovery of new form of matter, excitonium.
…when an electron, seated at the edge of a crowded-with-electrons valence band in a semiconductor, gets excited and jumps over the energy gap to the otherwise empty conduction band, it leaves behind a “hole” in the valence band. That hole behaves as though it were a particle with positive charge, and it attracts the escaped electron. When the escaped electron with its negative charge, pairs up with the hole, the two remarkably form a composite particle, a boson—an exciton.
“An exciton is a bound state of an electron and an electron hole which are attracted to each other by the electrostatic Coulomb force. It is an electrically neutral quasiparticle that exists in insulators, semiconductors and in some liquids.”
If excitons are found in water, the speed of light on contact with water could be linked to the quantized energy-dependent de novo creation of all biodiversity on Earth via the pheromone-controlled physiology of reproduction in all living genera. That fact led me to find information that links thermodynamic cycles of energy-dependent RNA-mediated protein folding chemistry to hydrophobicity in supercoiled DNA.
The book is organized into 4 sections on water, food, energy, and the future of sustainability, highlighting the interplay among these topics. The first section emphasizes water desalination, water management, and wastewater treatment. The second section discusses cereal processing, sustainable food security, bioenergy in food production, water and energy consumption in food processing, and mathematical modeling for food undergoing phase changes. The third section discusses fossil fuels, biofuels, synthetic fuels, renewable energy, and carbon capture. Finally, the book concludes with a discussion of the future of sustainability, including coverage of the role of molecular thermodynamics…
See for comparison. There is no coverage of the role of molecular thermodynamics in the symbols used to represent different religions. It’s as if the differences exist outside the context of what is known about the creation of the sun’s anti-entropic virucidal energy.
Energy-dependent changes in base pairs have since been linked from changes in the microRNA/messenger RNA balance and RNA editing to fixation of RNA-mediated amino acid substitutions that differentiate the cell types of all living genera. However, there appears to be no mention of how the virus-driven degradation of messenger RNA has been linked from mutations to all pathology in Guidelines for Genome-Scale Analysis of Biological Rhythms (2017).
Genome biology approaches have made enormous contributions to our understanding of biological rhythms, particularly in identifying outputs of the clock, including RNAs, proteins, and metabolites, whose abundance oscillates throughout the day. These methods hold significant promise for future discovery, particularly when combined with computational modeling. However, genome-scale experiments are costly and laborious, yielding “big data” that are conceptually and statistically difficult to analyze. There is no obvious consensus regarding design or analysis. Here we discuss the relevant technical considerations to generate reproducible, statistically sound, and broadly useful genome-scale data. Rather than suggest a set of rigid rules, we aim to codify principles by which investigators, reviewers, and readers of the primary literature can evaluate the suitability of different experimental designs for measuring different aspects of biological rhythms.
We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.
If the guidelines for linking the anti-entropic virucidal energy of sunlight to all biodiversity on earth via the physiology of pheromone-controlled reproduction in species from microbes to humans were applied, the guidelines could be extended to claims about the Molecular and cellular reorganization of neural circuits in the human lineage
…the dopaminergic interneurons found in the human neocortex were absent from the neocortex of nonhuman African apes. Such differences in neuronal transcriptional programs may underlie a variety of neurodevelopmental disorders.
Researchers found one gene, ZP2, was active in only human cerebellum — a surprise, said the researchers, because the same gene had been linked to sperm selection by human ova.
That claim can be placed into the context of what we detailed about energy-dependent RNA-mediated cell type differentiation in the molecular epigenetics section of our 1996 Hormones and Behavior review.
See: From Fertilization to Adult Sexual Behavior (1996)
Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans…
In the cytoplasm, small RNAs can control mammalian translation by regulating the stability of mRNA. In the nucleus, small RNAs can also control transcription and splicing. The mechanisms for RNA-mediated nuclear regulation are not understood and remain controversial, hindering the effective application of nuclear RNAi and investigation of its natural regulatory roles.
The tractable changes in organized genomes can be viewed in the context of The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression (2014)
The link to sperm selection by human ova establishes the role of quantized energy as information in the context of the physiology of reproduction, which protects all species from the virus-driven degradation of messenger RNA.
The link from the dopaminergic neuronal system to feedback loops that biophysically constrain behavior have been placed into the context of the transition from adolescence to adulthood. Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults
The authors fail to mention that Val158Met function is known to be affected by a functional single nucleotide polymorphism (SNP) in COMT (G-to-A base-pair substitution) leading to a methionine (Met) valine (Val) substitution at codons 108/158 (COMT Val158Met). Carriers of the Met allele have been found to display a fourfold decrease in enzymatic activity compared to Val allele carriers going along with an increase of prefrontal DA activity (Lachman et al. 1996; Lotta et al. 1995).
The degrading enzyme catechol-O-methyltransferase (COMT), determines dopamine availability in the prefrontal cortex. Thermostablility and exploratory behavior link the difference in the valine allele and the methionine allele to difference in primate brain development and behavior. That fact links the Second Law of Thermodynamics to one energy-dependent base pair change and the creation of one enzyme to changes in the microRNA/messenger RNA balance that link natural selection for energy-dependent codon optimality to one amino acid substitution that differentiates the cell types of the brain in different species of primates. Dobzhansky (1973) presciently placed that fact into this context:
…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.
The direction and speed of the evolution of any group of organisms at any given time is the resultant of the interaction of a series of reasonably well known factors and processes, both hereditary and environmental. The task of the evolutionist, therefore, is to seek out and evaluate all these factors and processes in respect to as many different organisms as possible, and from the specific information thus acquired construct such generalizations and hypotheses as he can. This requires the broadest possible knowledge of biology, which, if it cannot be acquired through direct contact with original research, must be built up vicariously through communication with biologists in different fields. — G. Ledyard Stebbins, Jr., ‘Preface’, Variation and Evolution in Plants, 1950.
…if you don’t have this enzyme, then this error-free repair is stopped. You can’t do it. If you can’t do the error-free repair, among other things that happen is that you expect these cells to be cancer prone.
In retrospect, we were totally blinded by our belief [in our findings]…we were not as careful or rigorous as we should have been (and as Tivoli was) in interpreting these experiments.
They touted their belief in the emergence and the evolution of all biodiversity on Earth.
As I was preparing this post, a long-term business partner called to tell me he was ending his efforts to sell human pheromone-enhanced fragrance products to those who understand how the products help to biophysically constrain viral latency in all mammals. Not enough people understand biologically-based cause and effect, which limits the market for anything that protects the organized genomes of people from the virus-driven degradation of messenger RNA.
A study of the influence of pheromone stressor(s) on proliferating germ and somatic cells was performed on laboratory lines of house mouse in the context of the physiological hypothesis of mutation process, proposed by M.E. Lobashev in 1947. Data from experiments are presented, and results obtained during last 10-15 years are discussed. The adaptive role of cytogenetic and other observed pheromonal effects is considered. The possible existence of interorganism systems of genetic regulation is discussed, the search for and study of which may help in more complete understanding of the regularities of functioning of genetic material.
My business partner and I discussed the obvious fact that most people do not want to learn anything about preventative medicine or effective treatments for all pathology, and that most are willing to accept what they are told by “pill-pushing” medical practitioners. The medical practitioners will not tell them that feedback loops link food odors and pheromones to the biophysically constrained pathways of healthy longevity. The medical practitioners will not tell people that vaccines and drug therapies alter the feedback loops. The vaccines and drug therapies act on the energy-dependent creation of the same enzymes linked from the creation of sunlight to all biodiversity on Earth.
In mammals, this is manifested in links from what offspring ingest to their food energy-dependent pheromone-controlled survival. See for example: MicroRNAs: Milk’s epigenetic regulators
The deficiency of exosomal miRNAs in infant formula and the persistent uptake of milk miRNAs after the nursing period via consumption of cow’s milk are two epigenetic aberrations that may induce adverse long-term effects on human health.
It has been more that two decades since publication of The Scent of Eros: Mysteries of Odor in Human Sexuality. We linked the pheromones from mother’s milk to the mother-infant bond and to adult behaviors. I am disappointed to admit that all experimental evidence of biologically-based cause and effect has been ignored by theorists who tout emergence and mutation-driven evolution.
Apparently, Nothing can stop them! They do not seem to realize that Dobzhansky’s “light of evolution” was sunlight and it linked ecological variation to ecological adaptation in all living genera via the pheromone-controlled physiology of reproduction.
For example, the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla (p. 127).
This is the four page booklet that explains the science in Cytosis. It was written and edited collaboratively by 20 PhD’s and Doctors through the world.
Please take some time to learn what happens to biologically uninformed theorists when serious scientists collaborate.
The collaborators achieved their common goal. The link from the creation of the sun’s anti-entropic virucidal energy to ATP and the creation of RNA is clear to players 10y/o +. The link from the virus-driven degradation of messenger RNA to all pathology in species from microbes to humans is equally clear..
Simply put 1) What organisms eat links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency.
Simply put 2) Food odors and species-specific pheromones biophysically constrain viral latency.
Simply put 3) Feedback loops typically prevent the hecatombic evolution of pathology that starts with viruses in seawater or the viruses in bacteria that eat electrons and produce uranium isotopes.
You may not believe that the sun was created and may not think that electrons were created to be eaten. Winners of this game will not care what losers believe. Losers can compare what they believe about the evolution of hydrogen and all biodiversity to the facts known to serious scientists who helped to create this game.
See also:
A rendering of how changes in an electron’s motion (bottom view) alter the scattering of light (top view), as measured in a new experiment that scattered more than 500 photons of light from a single electron. Previous experiments had managed to scatter no more than a few photons at a time. Credit: Extreme Light Laboratory|University of Nebraska-Lincoln
The free-energy principle (FEP) is a formal model of neuronal processes that is widely recognised in neuroscience as a unifying theory of the brain and biobehaviour. More recently, however, it has been extended beyond the brain to explain the dynamics of living systems, and their unique capacity to avoid decay.
They don’t understand the question that Schrodinger answered. He linked the anti-entropic virucidal energy of sunlight to the physiology of pheromone-controlled reproduction via what organisms eat. What they eat protects them from the virus-driven degradation of their messenger RNA. What they eat links food energy-dependent changes in base pairs from microRNA editing to RNA editing and fixation of RNA-mediated amino acid substitutions in organized genomes of all individuals of all living genera.
The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes of all living genera from virus-driven entropy. For example, protection of DNA from permanent UV damage occurs in the context of photosynthesis and nutrient-dependent RNA-directed DNA methylation, which links RNA-mediated amino acid substitutions to DNA repair. In the context of thermodynamic cycles of protein biosynthesis and degradation, DNA repair enables the de novo creation of G protein coupled receptors (GPCRs). Olfactory receptor genes are GPCRs. The de novo creation of olfactory receptor genes links chemotaxis and phototaxis from foraging behavior to social behavior in species from microbes to humans. Foraging behavior links ecological variation to ecological adaptation in the context of this atoms to ecosystems model of biophysically constrained energy-dependent RNA-mediated protein folding chemistry. Protein folding chemistry links nutrient-dependent microRNAs from microRNA flanking sequences to energy transfer and cell type differentiation in the context of adhesion proteins, and supercoiled DNA that protects all organized genomes from virus-driven entropy.
Life that is not protected from the virus-driven degradation of messenger RNA links the reduced number of food energy-dependent microRNAs to activation of the death gene. See for example:
The natural contribution of food energy is linked to the endogenous level of microRNA expression seen in neuronal cells in the context of limited cell death compared control glioblastoma cells. That fact was linked to the treatment of brain cancers.
For a review of how food energy-dependent microRNAs protect the organized genomes of all living genera from the virus-driven degradation of messenger RNA that links mutations to all pathology, see:
One factor that is not always taken into account when studying gene expression in the aged brain is the quality of the genetic material itself,” says Miller. “This variable is not necessarily related to any specific pathology or disease, but these results highlight the importance of properly controlling for RNA quality when studying the aged brain and indicate that degradation of genetic material may be an underappreciated feature of neurodegeneration or dementia.
Re: degradation of genetic material may be an underappreciated feature of neurodegeneration or dementia.
1) Does what organisms eat link food energy to RNA-directed DNA methylation and all healthy longevity via fixation of amino acid substitutions and transgenerational epigenetic inheritance in the context of the physiology of pheromone-controlled reproduction in species from microbes to humans?
2) Does the virus-driven theft of quantized energy link the loss of information from impaired methylation to all pathology?
The potential for sperm miRNA affecting zygote development has recently been reported in the literature [18] and has interesting implications for the use of sperm miRNA profiles as indicators of potential male fertility.
I suspect that Subatomic, like Cytosis, will help link atoms to ecosystems via my model of nutritional epigenetics and the pheromone-controlled visual perception of mass and energy, which has been linked from the sense of smell in bacteria across the space time continuum via olfaction.
Kohl is the co-author of “The Scent of Eros” and he is the creator of: The Scent of Eros and The Mind’s Eyes human pheromone-enhanced products. This is an excerpt from his presentation at the 2010 Annual Gathering of Mensa (i.e., the “high IQ” society).
Pheromones have since been linked from suicide prevention to the prevention of all neurodegenerative diseases and the prevention of all other pathology, which includes cancer prevention.
Everything known to serious scientists about biophysically constrained energy-dependent RNA-mediated cell type differentiation and viral latency in the context of quantum physics and the space time continuum will soon be known to everyone older than 10 who plays the game “Cytosis” and the game “Subatomic.”
In less than 3 hours of play-time, it will become clear that the virus-driven theft of quantized energy causes the degradation of messenger RNA, which links mutations to all pathology.
Eviatar Nevo: Our understanding of origin of life is very slim. . . . [First] life didn’t fossilize. The best we can know about origin of life may be from viruses we are looking at. They could have been at the origin of life before they parasitized it, or became symbionts in prokaryotes and eukaryotes. . . .
Young earth creationist / scientists put the virus-driven parasitism of life into the perspective of perfect creation in: Viral Genome Junk Is Bunk
“The most parsimonious answer is: the RNA viruses got their genes from their hosts.”6
The fact that viruses got their genes from their hosts became clear in the context of what is known about natural selection for energy-dependent codon optimality.
Revealing the determinants of codon usage bias is central to the understanding of factors governing viral evolution. Herein, we report the results of a survey of codon usage bias in a wide range of genetically and ecologically diverse human RNA viruses. This analysis showed that the overall extent of codon usage bias in RNA viruses is low and that there is little variation in bias between genes. Furthermore, the strong correlation between base and dinucleotide composition and codon usage bias suggested that mutation pressure rather than natural (translational) selection is the most important determinant of the codon bias observed. However, we also detected correlations between codon usage bias and some characteristics of viral genome structure and ecology, with increased bias in segmented and aerosol-transmitted viruses and decreased bias in vector-borne viruses. This suggests that translational selection may also have some influence in shaping codon usage bias.
In addition to spelling out protein sequence, mRNA codon triplets contain translation‐dependent regulatory information that influences transcript stability and contributes to controlled turnover of maternal mRNAs in frogs, mice, and flies.
Codon optimality forms a regulatory code within the genetic code that controls mRNA stability and translation efficiency.
Codon composition shapes maternal mRNA clearance during the maternal‐to‐zygotic transition in zebrafish, frog, mouse, and fly in a translation‐dependent manner.
Amino acid composition also influences mRNA stability in vertebrates.
Codon optimality correlates with codon bias, suggesting that codon optimality shapes steady‐state mRNA levels in homeostasis.
Excerpt:
The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease.
The sequence changes in the amino acid optimality code link energy-dependent changes in base pairs to fixation of amino acid substitutions in supercoiled DNA via the physiology of reproduction. The substitutions protect all organized genome from the virus driven degradation of messenger RNA that links mutations to all pathology.
The level of creativity required to link physics to chemistry and the conserved molecular mechanisms that link kinetic energy and food energy to RNA-mediated cell type differentiation via quantum mechanics and amino acid substitutions is exemplified in this moving sculpture and ignored by theorists who might unknowingly attribute all the interactions to mutations and evolution.
The group has been archived. No more comments will be added by those who lack the critical thinking skills required to link what organisms eat to the physiology of pheromone-controlled reproduction and all biodiversity.
It should be even clearer that two games “Cytosis” and “Subatomic” will put an end to any theoretical nonsense about mutations and evolution.
…rapid mRNA turnover starts with the energy-dependent de novo creation of microRNAs and ends with the virus-driven degradation of messenger RNA, which links mutations to all pathology.
In the early 1990’s, Bruce McEwen inspired my life’s works, which link the epigenetic effects of nutrient-stress and/or social stress to the fact that RNA biosynthesis is ATP-dependent. That fact helped all serious scientists link the virus-driven energy theft of quantized energy to the degradation of messenger RNA, which links mutations to all pathology.
We also identified that microRNA (miR)-18a inhibited translation of GR mRNA in cultured neuronal cells and that increased expression of miR-18a in the PVN was observed in F344 rats compared with SD rats. These strain differences in GR protein levels were not found in the hippocampus and prefrontal cortex, and the expression of miR-18a was much lower in these brain regions than in the PVN. Our results suggest that F344 rats could be a useful animal model for studying vulnerability to repeated stress, and that miR-18a-mediated down-regulation of GR translation may be an important factor to be considered in susceptibility to stress-related disorders.
Expression analyses of mRNAs of RE-1-containing genes and brain-enriched pre-microRNAs in the mPFC of the maternally separated rats. A, B, The expression of mRNAs (A) and pre-microRNAs (B) of a variety of RE-1-containing genes in the mPFC of AFR, HMS15, and HMS180 rats at P14 were quantified by Q-PCR (n = 6 for all groups). C, D, The expression of mature microRNAs in the mPFC of AFR, HMS15, and HMS180 rats at P14 were quantified by Northern blotting analysis (n = 5–6 for each group). E, The mRNA and pre-microRNA expression of RE-1-containing genes in the mPFC of adult AFR, HMS15, and HMS180 rats were quantified by Q-PCR (n = 6 for all groups). *p < 0.05.
Bruce McEwen subsequently linked what is known about energy-dependent changes in single nucleotide polymorphisms to effects of hormones on behavior in mice and humans via a food energy-dependent biophysically constrained amino acid substitution.
Excitatory amino acids play a key role in both adaptive and deleterious effects of stressors on the brain, and dysregulated glutamate homeostasis has been associated with psychiatric and neurological disorders. Here, we elucidate mechanisms of epigenetic plasticity… In WT mice after CRS and in unstressed mice with a BDNF loss-of-function allele (BDNF Val66Met), we show that the epigenetic activator of histone acetylation, P300, plays a pivotal role in the dynamic up- and down-regulation of mGlu2 in hippocampus via histone-3-lysine-27-acetylation (H3K27Ac) when acute stressors are applied. These hippocampal responses reveal a window of epigenetic plasticity that may be useful for treatment of disorders in which glutamatergic transmission is dysregulated.
The rapid mRNA turnover starts with the energy-dependent de novo creation of microRNAs and ends with the virus-driven degradation of messenger RNA, which links mutations to all pathology.
“Sometimes it is hard to believe that scientists could have unknowingly worked with methods that produce inconsistent results for almost 30 years”, says Becskei.
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
The fact that some researchers still do not know that the synthesis of RNA is energy-dependent makes it impossible for them to link virus-driven energy theft from the degradation of messenger RNA to mutations and all pathology in all living genera.
“…a mesmerising, perspective-shaking glimpse at Earth’s life-giving star.” (video)
Questions:
1) Did the energy in this life-giving star create itself?
2) How is hydrogen-atom transfer in DNA base pairs in solution biophysically constrained.
3) Who created the feedback loops that link the solar analemma from the time-space continuum to representations of biophysically constrained life and free will in the Mobius strip.
4) Was Linda Buck the first Nobel Laureate to establish the link from the food energy-dependent pheromone-controlled physiology of reproduction to biodiversity in all living genera?
5) Are biologically uninformed theorists capable of answering any questions about the energy of life or how virus-driven energy theft causes the degradation of messenger RNA that links constraint-breaking mutations to all pathology? The Mobius strip and the solar analemma exemplifie biophysical constraints on life history events.
The Mobius strip (above) is a visual aid for those who do not understand the concept of how free will is connected to the conserved molecular mechanisms of biophysically constrained energy-dependent RNA-mediated cell type differentiation in all living genera. If you cannot answer all 5 questions about energy in the context of the visual aid, which links the solar analemma to choices between quantized energy-dependent life and death, please search for microRNA on PubMed. The sun’s anti-entropic virucidal energy is biophysically constrained in microRNAs at every level of examination from angstroms to ecosystems.
If you cannot find the answers to any of the five questions about energy, ask a theorist to answer the first question. Alternatively, see: Computational identification of mutually homologous Zika virus miRNAs that target microcephaly genes
…ZIKV may modulate the action of various miRNAs, and miR-1304 in particular, resulting in microcephaly.
A SEC-MALS-RI or UV with DLS system extends the characterization range of biomolecules to glycoproteins, PEGylated proteins, hydrophobic proteins, biopolymers, and other biomolecules.
My summary: The “Brownian” motion of molecules links dynamic light-scattering (DLS) from ecological variation to ecological adaptations via Ultraviolet-visible (UV-Vis) spectroscopy. Detection of energy as information has been placed into the context of virucidal light as energy.
Dynamic light scattering (DLS) is a technique in physics that can be used to determine the size distribution profile of small particles in suspension or polymers in solution.[1] In the scope of DLS, temporal fluctuations are usually analyzed by means of the intensity or photon auto-correlation function (also known as photon correlation spectroscopy or quasi-elastic light scattering).
See also: Detection Limits of DLS and UV-Vis Spectroscopy in Characterization of Polydisperse Nanoparticles Colloids My summary: Ultraviolet-visible (UV-Vis) spectroscopy links the the food energy-dependent pheromone-controlled physiology of reproduction to the weekend resurrection of the bacterial flagellum in P. fluorescens, which responds to the light-activated chemistry of life with fluorescence even after the “knock-out” of the gene for its mobility, which was resurrected over the weekend as reported in: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system
The resurrection in this organism, links its fluorescence to quantized energy-dependent exosome-delivered microRNAs, which have been reported to be Ultraconserved Elements in the Human Genome. When theorists use terms like ultraconserved elements outside the context of the conserved energy in microRNAs, it is clear that theorists are attempting to obfuscate this fact: The energy-dependent de novo creation of microRNAs has been linked to all biodiversity in all living genera via the physiology of pheromone-controlled reproduction.
See for example: All in the (bigger) family I wrote:
The 2015 Society for Integrative and Comparative Biology (SICB) presenters may not recognize how much progress has been made since the 2013 ecological epigenetics symposium. For example, since then authors claimed “…ctenophore neural systems, and possibly muscle specification, evolved independently from those in other animals.” http://dx.doi.org/10.1038/nature13400
Six months later, other authors traced signaling factors found in vertebrates to the origin of nerve cell centralization via the diffuse nerve net of animals like the sea anemone. http://dx.doi.org/10.1038/ncomms6536 That fact suggests ecological variation is linked to ecological adaptations in morphological and behavioral phenotypes via signaling protein concentrations that differentiate various cell types in body axes and the central nervous system.
Links across species from the epigenetic landscape to the physical landscape of DNA in organized genomes appear to have their origins in the conserved molecular mechanisms of RNA-directed DNA methylation and RNA-mediated protein folding. Two weeks after the publication that refuted ideas about independently evolved neural systems or muscle specification — and perhaps refuted the independent evolution of anything else, SICB presenters linked crustaceans to insects.
Apparently, they’ve learned that the same set of microRNAs controls expression of the genes for rate-limiting enzymes that control the hormone production of different hormones in insects and crustaceans.
Why were they left with any questions about how crustaceans and insects could all be part of one big family? They linked RNA-mediated cell type differentiation to what we described in our section on molecular epigenetics in our 1996 Hormones and Behavior review. From Fertilization to Adult Sexual Behavior
The interactions of these small noncoding RNAs in such primitive species have wide-reaching effects, from increasing viral and bacterial proliferation, better responses to stress, increased virulence, to manipulation of host immune responses…
A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
Stop playing the ridiculous games of theorists who have failed to link the Creation of the sun’s quantized energy to all biodiversity on Earth. Theorists also failed to link the virus-driven degradation of messenger RNA from mutations to all pathology. Instead, they have used definitions of terms and definitions of species that are not limited to that fact that all organisms on Earth must eat or they fail to reproduce.
See for examples of pseudoscientific nonsense: New Research Problem of Species Definitions
Darwin first noted that there is no one definition of species, and not much has changed since then.
All species-specific behavior is food energy-dependent and RNA-mediated cell type differentiation biophysically constrains it in the context of the physiology of pheromone-controlled reproduction in all living genera. Darwin presciently included that fact in his “conditions of life.” He warned others that they could not start with natural selection, but many others have consistently ignored Darwin’s warnings. They also ignore the consistency of biological facts that link what organisms eat to the survival of all species via the pheromone-controlled physiology of reproduction. That forces them to ignore the consequences of virus-driven energy theft.
See: Virus-mediated archaeal hecatomb in the deep seafloor
We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.
…the clear identity and easy alignment of these sequences makes them good candidates for estimating phylogeny, and they can reliably be found and identified across all members of a clade of interest. Their relatively slow evolution [3] also means that they can easily be identified in de novo assemblies of genomes.
The intrinsic ability of neurogenesis after stroke has been proven weak, which results in insufficient repair of injury in the nerve system. Recent studies suggest multiple microRNAs (miRNAs) are involved in the neuroremodeling process. Targeted miRNAs delivery for amplification of neurogenesis is promising in promoting the prognosis after ischemia. Here, we showed that modified exosomes, with rabies virus glycoprotein (RVG) fused to exosomal protein lysosome-associated membrane glycoprotein 2b (Lamp2b), could efficiently deliver miR-124 to the infarct site. Systemic administration of RVG-exosomes loaded with miR-124 promoted cortical neural progenitors to obtain neuronal identity and protect against ischemic injury by robust cortical neurogenesis. Our study suggests that RVG-exosomes can be utilized therapeutically for the targeted delivery of gene drugs to the brain, thus having great potential for clinical applications.
The elucidation of the mechanisms by which specific compounds influence cell proliferation and neurogenesis, and eventually reproductive conditions in males and females should provide further insight as to how the odor environment controls and modulates the reproductive activities of animals.
See also: Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
Clearly, researchers who use viruses to stimulate neurogenesis have not learned that all cell type differentiation is energy-dependent and controlled by feedback loops. Their use of viruses will continue ot link virus-driven energy theft from the degradation of messenger RNA to all pathology via the constraint breaking mutations the Masatoshi Nei, and many other biologically uninformed theorists have included in their stories about Mutation-Driven Evolution.
The functional relevance of exosomes in many different biological systems, including the immune system, is beginning to be demonstrated5,6,7,8,9,10,11.
…the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. The role of the microRNA/messenger RNA balance (Breen, Kemena, Vlasov, Notredame, & Kondrashov, 2012; Duvarci, Nader, & LeDoux, 2008; Griggs et al., 2013; Monahan & Lomvardas, 2012) in adaptive evolution will certainly be discussed in published works that will follow.
It has been assumed that DNA synthesis by the leading- and lagging-strand polymerases in the replisome must be coordinated to avoid the formation of significant gaps in the nascent strands.
What looks like coordination is actually the outcome of a random process of starting, stopping and variable speeds. Over time, any one DNA polymerase will move at an average speed; look at a number of DNA polymerases synthesizing DNA strands over time, and they will have the same average speed.
…the metabolic enzyme, pyruvate kinase muscle (PKM), interacts with sub-pools of endoplasmic reticulum (ER)-associated ribosomes, exerting a non-canonical function as an RNA-binding protein in the translation of ER-destined mRNAs.
Metabolism is food energy-dependent. That fact should have eliminated all the pseudoscientific nonsense about the random process of starting, stopping and variable speeds. For example, autophagy is quantized energy-dependent and the energy from food protects all organized genomes from virus-driven energy theft and the degradation of messenger RNA that links mutations to all pathology.
See also: The evolution of ecosystem ascendency in a complex systems based model
Abstract conclusion:
Our findings support the validity of ecosystem ascendency as a meaningful measure of ecosystem organisation, which increases over evolutionary time scales and significantly drops during periods of disturbance. The results suggest a general trend towards both higher integrity and increased stability driven by functional and structural ecosystem coadaptation.
Ecosystem ascendancy is food energy-dependent and biophysically constrained by the pheromone-controlled physiology of reproduction in all living genera.
Attempts to model general trends towards the increased stability of functional and structural ecosystems without linking the anti-entropic virucidal energy of sunlight to the physiology of reproduction are examples of what Richard Feynman referred to as human idiocy.
Richard Feynman was a Nobel prize winning Theoretical Physicist who popularized physics with his entertaining lecture style. This snippet is taken from one of his lectures in the series “The character of Physical Law” where he complains about all the different units that are used to measure the single concept of Energy.
See also: Structural diversity of supercoiled DNA
Six decades after the elucidation of its double helical structure, DNA continues to surprise us by revealing new information. Our cryo-ET, biochemical, and computational studies show the astounding versatility and dynamism of DNA depending on the degree of supercoiling. DNA simultaneously exists in a largely inactive B-form with bases tucked in and protected and an active, highly varied structure with exposed bases. Our data provide relative comparisons of supercoiling-dependent twisted, writhed, curved, and kinked conformations and associated base exposure. Each of these structural features may be differentially recognized by the proteins, nucleic acids, and small molecules that modulate DNA metabolic processes.
See for comparison: 7/25/13
Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution. 7/26/13
Jay R. Feierman: I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that “Random mutations are the substrate upon which directional natural selection acts” is a correct and true statement. See also:These groups are moderated by Robert Karl Stonjek, who is an example of human idiocy. He knows nothing about biophysically constrained energy-dependent cell type differentiation and consistently displays his ignorance by limiting ability to explain the role that the virus-driven degradation of messenger RNA plays in all pathology. Psychiatry and Clinical Psychology Neuroscience Evolutionary Psychology News Religion: Science and Psychology Paleoanthropology Studies Quantum Physics News
On his FB group for discussion of Sensescence on 6/16/17 I wrote:
All death is caused by trauma or the virus driven degradation of messenger RNA
On 6/17/17 Robert Karl Stonjek wrote (with my emphasis):
Or viruses, or bacteria, or degenerative disease, or genetic disease (there are many), or substance abuse (there are many), or obesity, or….the only one I can’t find in the regular literature is virus driven degradation of messenger RNA.
And then: Robert Karl Stonjek turned off commenting for this post. Can you die from old age?
The pervasive ignorance of those who moderate or censor the comments made by serious scientists via social media has overwhelmed all attempts to present what is known about the virus-driven degradation of messenger RNA, which causes the mutations that have been linked to all pathology.
See for comparison:
…while Chinese-born scientists who trained in the United States used to stay here to work, they are now going back to China after their education is over.
Had she stayed in the United States, she would have been subjected to pseudoscientific nonsense like this:
Still, even in fruit flies, other sensory input besides pheromones — acoustic, tactile, and visual stimuli — play a role in sexual attraction, and sex specific responses to these stimuli appear to be innate rather than learned by association [36.]. We simply don’t know where the boundary between prespecified attraction and learned association lie in our own species, nor do we have compelling evidence for the primacy of one sense over another.” — Simon LeVay (2011) in his comments on my award-winning model – after it won a second award in 2007. See: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences
See also:
… chemosignal enthusiasts point to a variety of studies in which sniffing body secretions or substances purified from secretions appears to have some psychological effect…” — Simon LeVay (2016)
It does not surprise me that senior author Wen Zhou has since linked the sense of smell to the time-space continuum. She was the most promising student I ever met, and I was sad to see her return to China after developing her expertise in the context of what she learned from Denise Chen, who learned about olfaction and pheromones from Martha McClintock.
Earlier this year, Wen Zhou’s group showed that olfaction alters the perception of the space-time continuum, which also is warped by the distribution of mass and energy. She has helped to show how food energy and the pheromone-controlled physiology of reproduction are linked to energy-dependent subjective time. For comparison, theorectical physicists have failed to explain anything in the context of multisensory inputs. That is why I frequently refer to biologically uninformed theoretical physicists in the same context as the biologically uninformed neo-Darwinian theorists who have failed to link quantized energy to all healthy longevity and failed to link virus-driven energy theft from the degradation of messenger RNA to mutations and all pathology.
Simply put, the multisensory inputs link quantized energy as information from the epigenetic landscape to the physical landscape of DNA at subsecond scales via neural energy and RNA-mediated amino acid substitutions.
The subsecond scales links femtosecond blasts of UV light to DNA repair, which is required to link quantum physics to quantum souls. That is the topic of my next interview with J.A. Parker, who sent me the questions in advance, so that I could try to keep the jargon to a minimum.
Words that originally had only concrete or external meaning have grown to also have meaning in the realms of the abstract and internal.
Who else besides Schrodinger in “What is Life? (1944) and J.A. Parker of Quantum Souls knew that Dobzhansky’s “light of evolution” would be traced back to “Let there be Light” in Biblical Genesis via what is known about the anti-entropic virucidal energy of sunlight?
