Posts tagged: viruses

Happy New Year! In 2018, serious scientists are prepared to help you prevent or effectively treat all pathology. We have nearly stopped the pseudoscientific nonsense touted by theorists — although some of them didn’t get the memo from 1968, which is when Frohlich published: Long-range coherence and energy storage in biological systems.
He linked certain processes in living systems from the creation of energy to hydrogen bonds in cell membranes and to dipolar oscillations that link the creation of the sense of smell in bacteria from the physiology of pheromone-controlled reproduction to all biodiversity via the creation of ATP; the creation of RNA, and fixation of energy-dependent RNA-mediated amino acid substitutions.
See: The vibrational theory of olfaction for the win
Historical perspective, based on Frohlich’s “speculation.”
From Fertilization to Adult Sexual Behavior (1996)

Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation…

The sexual differentiation of cell types protects them from the virus-driven theft of quantized energy, which Frohlich linked to the degradation of the cell wall and what is now known about how unicellular bacteria become archaea before they become L-forms.
See: Cytosis: A Cell Biology Board Game

A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!

Food energy-dependent pheromone-controlled biophysically constrained viral latency keeps egg cells fresh in the context of autophagy and sexual differentiation. Biophysical constraints prevent the transgenerational epigenetic inheritance of virus-driven pathology, which is caused by the virus-driven theft of quantized energy that links the degradation of messenger RNA to all pathology.
See for comparison: Keeping egg cells fresh with epigenetics (2017)
As soon as the Medical Xpress news source realized that they had destroyed neo-Darwinian pseudoscientific nonsense with their report on epigenetics, the post went missing.

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They cited: Courtney W. Hanna et al, MLL2 conveys transcription-independent H3K4 trimethylation in oocytes, Nature Structural & Molecular Biology (2017). DOI: 10.1038/s41594-017-0013-5
The cited work is not yet available at the DOI: I attempted to add this comment:
The speed of light on contact with water links food energy to the physiology of pheromone-controlled reproduction and all biophysically constrained biodiversity. Now, there is a mathematical model that refutes neo-Darwinism and “Big Bang” cosmology. Use it to make all biologically uninformed theorists recognize their foolishness. Quantum Vacuum Dynamics, Coherence, Superluminal Photons and Hypercomputation in Brain Microtubules
The human idiocy exposed by Courtney W. Hanna et al (2017?) was also exposed at least twice in September. See: Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells Published online 2017 Sep 25

See why Feynman was forced to comment on the facts about food energy, years before this information became generally known: Trinucleotide Repeats: Fragile X Syndrome

DNA (deoxyribonucleic acid)… contains a “code” of 3-letter words known as “codons” or “trinucleotides.” Many genes normally contain trinucleotide sequences that can be repetitive. These are called “trinucleotide repeats.” But when the number of trinucleotide repeats increases to a larger than normal number of copies, the DNA is changed. The gene may not function as it should, or may not work at all.

…extra trinucleotide repeats cause the DNA to become unstable, the repeats within that gene expand even more. The result is that the child has a gene that is not functioning properly (if at all), and the child is said to have the “full mutation.” An example of a trinucleotide repeat disorder is Fragile X syndrome.

See also: Researchers discover how cells remember infections decades later

On the surface and through the actions of their genes, they look like cells that have never been exposed to an infection, but on their DNA the researchers found a fingerprint, called a methylation pattern, that identifies them as having been through battle as an infection-fighting cell, which are called effector cells.

Thanks to passive-aggressive antagonist Jon Lieff for repeatedly bringing the difference between pseudoscientists and serious scientists to my attention. Pseudoscientists refer to “effector cells” so that the obvious link from food energy to autophagy to healthy longevity is obfuscated.
See for instance: Ancient Mutation may Help Explain Origin of Human Organs

1) Researchers have reported that a neutral mutation having no real purpose and occurring randomly over 700 million years ago may help to explain the origins of complex structures like organs in humans and other vertebrates.

The pseudoscientific nonsense reported by Labroots may have reached its peak.

2) The same gene can give rise to different proteins that can act in entirely different ways by editing those genes a little differently, in a phenomenon called alternative splicing…

A link to a video about alternative splicing is included; See: Alternative Splicing
Conclusion: 

“The new discovery confirms how versatile biological evolution is: the same foundation and gene tools can be used to build a wood cabin or a skyscraper,” concluded Garcia-Fernàndez.

There is no such thing as versatile biological evolution. It is long past time for serious scientists to stop the pseudoscientific nonsense touted by theorists.
For a reminder of how long serious scientists have known the facts about alternative splicing, see again:
From Fertilization to Adult Sexual Behavior (1996)

Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation…

Alternative splicing is food energy-dependent and RNA-mediated in the context of the physiology of pheromone-controlled biophysically constrained viral latency.
All niche construction is food energy-dependent and controlled by the physiology of reproduction.
See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model

This model details how chemical ecology drives adaptive evolution via: (1) ecological niche construction, (2) social niche construction, (3) neurogenic niche construction, and (4) socio-cognitive niche construction.

This model organism exemplifies how ecological variation must be linked to ecological adaptation in species from microbes to humans. See: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system

Under strong selection for motility, these bacteria consistently regained flagella within 96 hours via a two-step evolutionary pathway. Step 1 mutations increase intracellular levels of phosphorylated NtrC, a distant homolog of FleQ, which begins to commandeer control of the fleQ regulon at the cost of disrupting nitrogen uptake and assimilation. Step 2 is a switch-of-function mutation that redirects NtrC away from nitrogen uptake and toward its novel function as a flagellar regulator. Our results demonstrate that natural selection can rapidly rewire regulatory networks in very few, repeatable mutational steps.

This was reported in the context of the classic phrase from the Jurrasic Park series of movies: Life finds a way (video)
The claim that life finds a way to resurrect the bacterial flagellum over the weekend via mutations can be compared in the context of this model organism. See: The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche

…this model has identified a number of proregenerative signals, including growth factor signaling associated with nerves, and signals associated with the extracellular matrix (ECM) that induce pattern formation.

Educational video: Meet the creature that can regenerate its brain and resist cancer.
At the end of the video, the yin yang symbol from Chinese philosophy is superimposed over the electron cloud, which links the anti-entropic virucidal energy of sunlight to the physiology of pheromone-controlled reproduction and the viral latency that protects all organized genomes from the degradation of messenger RNA.
The virus-driven degradation of messenger RNA is clearly the link from mutations to all pathology, and all pathology can be examined in the context of the axolotyl model organism (aka: The “walking fish.”)
The portrayals of the “walking fish” as an example of neo-Darwinian evolution is a ridiculous example of what Feynman called human idiocy. Darwin place his “conditions of life” before natural selection because he knew that organisms must eat and reproduce. Neo-Darwinists assumed that the 2nd Law of Thermodynamics did not need to include any aspect of quantum entanglement.
Energy-dependent changes have since been linked from electrons to ecosystems by autophagy — the innate antiphage defense mechanism.
The defense mechanism protects the cell types of axolotyl and all other living genera from the virus-driven energy theft that links the destruction of the cell wall from bacteria to archaea and to L-forms, the last example on Earth of virus-driven energy theft and failed autophagy.